RPS6KB2 anticorps (C-Term)

N° du produit ABIN392546

Détail du produit anti-RPS6KB2 anticorps

Antigène: RPS6KB2 (Ribosomal Protein S6 Kinase, 70kDa, Polypeptide 2 (RPS6KB2))

Épitope: AA 452-482, C-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp RPS6KB2 est non-conjugé

Application: Western Blotting (WB)

Purification: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogène: This p70 S6Kbeta antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 452-482 amino acids from the C-terminal region of human p70 S6Kbeta.

Clone: RB0891

Isotype: Ig Fraction

Information d'application

Indications d'application: WB: 1:1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Date de péremption: 6 months

Références pour anticorps anti-RPS6KB2 (ABIN392546)

Wang, Li, Du, Xu, Wang, Zhang, Xu, Zeng, Mao, Cao: "The Class I PI3K inhibitor S14161 induces autophagy in malignant blood cells by modulating the Beclin 1/Vps34 complex." dans: Journal of pharmacological sciences, Vol. 134, Issue 4, pp. 197-202, (2018) (PubMed).

Kroczynska, Mehrotra, Majchrzak-Kita, Arslan, Altman, Stein, McMahon, Kozlowski, Kahle, Eklund, Fish, Platanias: "Regulatory effects of SKAR in interferon ? signaling and its role in the generation of type I IFN responses." dans: Proceedings of the National Academy of Sciences of the United States of America, Vol. 111, Issue 31, pp. 11377-82, (2014) (PubMed).

Cruz, Hedden, Boyer, Kharas, Fruman, Lee-Fruman: "S6 kinase 2 potentiates interleukin-3-driven cell proliferation." dans: Journal of leukocyte biology, Vol. 78, Issue 6, pp. 1378-85, (2005) (PubMed).

Détails sur RPS6KB2

Antigène: RPS6KB2 (Ribosomal Protein S6 Kinase, 70kDa, Polypeptide 2 (RPS6KB2))

Autre désignation: p70 S6Kbeta (RPS6KB2 Produits)

Synonymes: anticorps KLS, anticorps P70-beta, anticorps P70-beta-1, anticorps P70-beta-2, anticorps S6K-beta2, anticorps S6K2, anticorps SRK, anticorps STK14B, anticorps p70(S6K)-beta, anticorps p70S6Kb, anticorps 70kDa, anticorps ribosomal protein S6 kinase B2, anticorps ribosomal protein S6 kinase, polypeptide 2, anticorps RPS6KB2, anticorps Rps6kb2

Sujet: This gene encodes a member of the RSK (ribosomal S6 kinase) family of serine/threonine kinases. This kinase contains 2 nonidentical kinase catalytic domains and phosphorylates the S6 ribosomal protein and eucaryotic translation initiation factor 4B. Phosphorylation of S6 leads to an increase in protein synthesis and cell proliferation.

Poids moléculaire: 53455

ID gène: 6199

NCBI Accession: NP_003943

UniProt: Q9UBS0

Pathways: Signalisation PI3K-Akt, Signalisation RTK, AMPK Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway