BUB1B anticorps (N-Term)

N° du produit ABIN392627

Détail du produit anti-BUB1B anticorps

Antigène: BUB1B (Budding Uninhibited By Benzimidazoles 1 Homolog beta (Yeast) (BUB1B))

Épitope: AA 3-33, N-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp BUB1B est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purification: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogène: This BUBR1 (BUB1B) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 3-33 amino acids from the N-terminal region of human BUBR1 (BUB1B).

Clone: RB03121-03122

Isotype: Ig Fraction

Information d'application

Indications d'application: WB: 1:1000. IHC-P: 1:50~100

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Date de péremption: 6 months

Détails sur BUB1B

Antigène: BUB1B (Budding Uninhibited By Benzimidazoles 1 Homolog beta (Yeast) (BUB1B))

Autre désignation: BUBR1 (BUB1B) (BUB1B Produits)

Synonymes: anticorps BUB1beta, anticorps BUBR1, anticorps Bub1A, anticorps MAD3L, anticorps MVA1, anticorps SSK1, anticorps hBUBR1, anticorps AU045529, anticorps bub1b, anticorps BUB1, anticorps BUB1-like, anticorps BubR1, anticorps BubRI, anticorps CG14030, anticorps CG14030/Bub1, anticorps Dmel\\CG14030, anticorps bub1, anticorps BUB1 mitotic checkpoint serine/threonine kinase B, anticorps BUB1B, mitotic checkpoint serine/threonine kinase, anticorps BUB1B, mitotic checkpoint serine/threonine kinase L homeolog, anticorps Mitotic checkpoint serine/threonine-protein kinase BUB1 beta, anticorps Bub1 kinase, anticorps BUB1B, anticorps Bub1b, anticorps bub1b.L, anticorps bub1b, anticorps Bub1

Sujet: BUB1B, a member of the Ser/Thr protein kinase family, is a probable component of the mitotic checkpoint that delays anaphase until all chromosomes are properly attached to the mitotic spindle. It can interact with BUB3, CENP-F, CENP-E and mitosin, and can be localized to nuclear kinetochores. This protein is highly expressed in thymus and spleen. The CD1 domain directs kinetochore localization and binding to BUB3. The protein possesses a cyclin destruction box sequence, which targets protein for rapid degradation by ubiquitin-dependent proteolysis during the transition from mitosis to interphase. Defects in BUB1B are associated with tumor formation.

Poids moléculaire: 119545

ID gène: 701

NCBI Accession: NP_001202

UniProt: O60566