IKKi/IKKe anticorps (C-Term)

N° du produit ABIN392751

Détail du produit anti-IKKi/IKKe anticorps

Antigène: IKKi/IKKe (IKBKE) (Inhibitor of kappa Light Polypeptide Gene Enhancer in B-Cells, Kinase epsilon (IKBKE))

Épitope: AA 686-716, C-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp IKKi/IKKe est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purification: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogène: This IKK epsilon (IKKE) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 686-716 amino acids from the C-terminal region of human IKK epsilon (IKKE).

Clone: RB3912

Isotype: Ig Fraction

Information d'application

Indications d'application: WB: 1:1000. IHC-P: 1:50~100. IHC-P: 1:50~100

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Date de péremption: 6 months

Détails sur IKKi/IKKe

Antigène: IKKi/IKKe (IKBKE) (Inhibitor of kappa Light Polypeptide Gene Enhancer in B-Cells, Kinase epsilon (IKBKE))

Autre désignation: IKK epsilon (IKKE) (IKBKE Produits)

Synonymes: anticorps zgc:100844, anticorps IKBKE, anticorps MGC130907, anticorps IKK-E, anticorps IKK-i, anticorps IKKE, anticorps IKKI, anticorps AW558201, anticorps IKKepsilon, anticorps Ikki, anticorps inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon, anticorps inhibitor of nuclear factor kappa B kinase subunit epsilon, anticorps inhibitor of nuclear factor kappa B kinase subunit epsilon L homeolog, anticorps inhibitor of kappaB kinase epsilon, anticorps IKBKE, anticorps ikbke, anticorps ikbke.L, anticorps Ikbke

Sujet: Protein kinases are enzymes that transfer a phosphate group from a phosphate donor, generally the g phosphate of ATP, onto an acceptor amino acid in a substrate protein. By this basic mechanism, protein kinases mediate most of the signal transduction in eukaryotic cells, regulating cellular metabolism, transcription, cell cycle progression, cytoskeletal rearrangement and cell movement, apoptosis, and differentiation. With more than 500 gene products, the protein kinase family is one of the largest families of proteins in eukaryotes. The family has been classified in 8 major groups based on sequence comparison of their tyrosine (PTK) or serine/threonine (STK) kinase catalytic domains. The AGC kinase group consists of 63 kinases including the cyclic nucleotide-regulated protein kinase (PKA & PKG) family, the diacylglycerol-activated/phospholipid-dependent protein kinase C (PKC) family, the related to PKA and PKC (RAC/Akt) protein kinase family, the kinases that phosphorylate G protein-coupled receptors family (ARK), and the kinases that phosphorylate ribosomal protein S6 family (RSK).

Poids moléculaire: 80462

ID gène: 9641

NCBI Accession: NP_001180250, NP_001180251, NP_054721

UniProt: Q14164

Pathways: Signalisation TLR, Activation of Innate immune Response, Hepatitis C, Toll-Like Receptors Cascades