You are viewing an incomplete version of our website. Please click to reload the website as full version.

SETDB2 anticorps (SET Domain, Bifurcated 2) (AA 620-720)

Détail du produit anti-SETDB2 anticorps No. ABIN393380, Fournisseur: Connectez-vous pour afficher
Antigène
  • C13orf4
  • CLLD8
  • Clld8
  • CLLL8
  • Gm293
  • KMT1F
Épitope
AA 620-720
30
8
6
3
3
1
1
1
Reactivité
Humain
68
19
16
6
5
5
1
Hôte
Souris
28
23
17
Clonalité (Clone)
Monoclonal ()
Conjugué
Cet anticorp SETDB2 est non-conjugé
4
4
4
3
3
3
1
1
1
1
1
1
1
1
1
Application
Western Blotting (WB)
55
40
11
3
2
2
1
1
Fournisseur
Connectez-vous pour afficher
Supplier Product No.
Connectez-vous pour afficher
Request

Ce produit gratuit

Envoyez-nous votre proposition de validation. J'aimerais valider ce produit

Savoir plus

Images

Immunogène SETDB2 (NP_114121, 620 a.a. ~ 720 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 K
Clone 1E2
Isotype IgG2a kappa
Specificité SETDB2 (NP_114121, 620 a.a. ~ 720 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Purification Purified
Autre désignation SETDB2 (SETDB2 Antibody Extrait)
Sujet Proteins that contain a SET domain, such as SETDB2, modulate gene expression epigenetically through histone H3 (see MIM 601128) methylation. SETDB2 is likely a histone H3 methyltransferase, as it contains both the active site and flanking cysteine residues required for catalytic activity (Zhang et al., 2003 [PubMed 12754510]).
Synonyms: C13orf4, CLLD8, CLLL8, DKFZp586I0123, DKFZp761J1217 SET domain, bifurcated 2
Poids moléculaire 81894 DA
ID gène 83852
NCBI Accession NP_114121
Domaine de recherche Signaling, Protein Modifications, Chromatin, Cell Structure
Indications d'application Western blot = 1:500-1000
Commentaires

Background: Proteins that contain a SET domain, such as SETDB2, modulate gene expression epigenetically through histone H3 (see MIM 601128) methylation. SETDB2 is likely a histone H3 methyltransferase, as it contains both the active site and flanking cysteine residues required for catalytic activity (Zhang et al., 2003 [PubMed 12754510]).

Restrictions For Research Use only
Buffer Phosphate buffered saline, pH 7.2
Stock 4 °C/-20 °C
Stockage commentaire Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles
Date de péremption 6 months
Supplier Images
Western Blotting (WB) image for anti-SETDB2 anticorps (SET Domain, Bifurcated 2) (AA 620-720) (ABIN393380) SETDB2 monoclonal antibody (M07), clone 1E2. Western Blot analysis of SETDB2 expressi...
Reference: Background Falandry, Fourel, Galy, Ristriani, Horard, Bensimon, Salles, Gilson, Magdinier: "CLLD8/KMT1F is a lysine methyltransferase that is important for chromosome segregation." dans: The Journal of biological chemistry, Vol. 285, Issue 26, pp. 20234-41, 2010 (PubMed).

Genuneit, Cantelmo, Weinmayr, Wong, Cooper, Riikjärv, Gotua, Kabesch, von Mutius, Forastiere, Crane, Nystad, El-Sharif, Batlles-Garrido, García-Marcos, García-Hernández, Morales-Suarez-Varela, Nilsson, Bråbäck, Saraçlar, Weiland, Cookson, Strachan, Moffat: "A multi-centre study of candidate genes for wheeze and allergy: the International Study of Asthma and Allergies in Childhood Phase 2." dans: Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology, Vol. 39, Issue 12, pp. 1875-88, 2010 (PubMed).

Kimura, Wakamatsu, Suzuki, Ota, Nishikawa, Yamashita, Yamamoto, Sekine, Tsuritani, Wakaguri, Ishii, Sugiyama, Saito, Isono, Irie, Kushida, Yoneyama, Otsuka, Kanda, Yokoi, Kondo, Wagatsuma, Murakawa et al.: "Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. ..." dans: Genome research, Vol. 16, Issue 1, pp. 55-65, 2006 (PubMed).

Gerhard, Wagner, Feingold, Shenmen, Grouse, Schuler, Klein, Old, Rasooly, Good, Guyer, Peck, Derge, Lipman, Collins, Jang, Sherry, Feolo, Misquitta, Lee, Rotmistrovsky, Greenhut, Schaefer, Buetow et al.: "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). ..." dans: Genome research, Vol. 14, Issue 10B, pp. 2121-7, 2004 (PubMed).

Dunham, Matthews, Burton, Ashurst, Howe, Ashcroft, Beare, Burford, Hunt, Griffiths-Jones, Jones, Keenan, Oliver, Scott, Ainscough, Almeida, Ambrose, Andrews, Ashwell, Babbage, Bagguley, Bailey et al.: "The DNA sequence and analysis of human chromosome 13. ..." dans: Nature, Vol. 428, Issue 6982, pp. 522-8, 2004 (PubMed).