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Merlin anticorps (Internal Region)

NF2 Reactivité: Poisson zèbre (Danio rerio) IHC (p), EIA Hôte: Chèvre Polyclonal unconjugated
N° du produit ABIN401528
  • Antigène Voir toutes Merlin (NF2) Anticorps
    Merlin (NF2) (Neurofibromin 2 (NF2))
    Épitope
    • 28
    • 15
    • 9
    • 7
    • 6
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Internal Region
    Reactivité
    • 77
    • 65
    • 53
    • 5
    • 4
    • 4
    • 4
    • 4
    • 4
    • 3
    • 3
    • 2
    • 1
    Poisson zèbre (Danio rerio)
    Hôte
    • 88
    • 4
    • 1
    Chèvre
    Clonalité
    • 90
    • 3
    Polyclonal
    Conjugué
    • 47
    • 5
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    Cet anticorp Merlin est non-conjugé
    Application
    • 71
    • 30
    • 27
    • 26
    • 19
    • 17
    • 11
    • 11
    • 6
    • 4
    • 3
    • 1
    • 1
    Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
    Séquence
    C-EKSKHLQDQL K
    Specificité
    This antibody detects Neurofibromin 2 (Internal).
    Réactivité croisée (Details)
    Species reactivity (tested):Zebrafish
    Purification
    Ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide
    Immunogène
    Peptide from the internal region of the protein sequence according to NP_998116.1 . Genename: nf2
    Top Product
    Discover our top product NF2 Anticorps primaire
  • Indications d'application
    Peptide ELISA: antibody detection limit dilution 1: 32000. Immunohistochemistry: This product has been successfully used by customers onFormalin/PFA-fixed paraffin-embedded sections of Zebrafish Brain Cortex.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Restrictions
    For Research Use only
  • Concentration
    0.5 mg/mL
    Buffer
    Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Conseil sur la manipulation
    Avoid repeated freezing and thawing.
    Stock
    4 °C/-20 °C
    Stockage commentaire
    Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C.
  • Antigène
    Merlin (NF2) (Neurofibromin 2 (NF2))
    Autre désignation
    Merlin (NF2 Produits)
    Synonymes
    anticorps ACN, anticorps BANF, anticorps SCH, anticorps NF2, anticorps merlin, anticorps zgc:194620, anticorps zgc:194631, anticorps NF2a, anticorps nf2, anticorps neurofibromin 2, anticorps neurofibromin 2a (merlin), anticorps neurofibromin 2b (merlin), anticorps neurofibromin 2 (merlin) S homeolog, anticorps NF2, anticorps Nf2, anticorps nf2a, anticorps nf2b, anticorps nf2.S
    Sujet
    Neurofibromin 2 (NF2) is a tumor suppressor gene encoding the protein Merlin. Merlin is closely related to the ERM (ezrin, radixin, moesin) family of proteins. The precise funtion of Merlin is not clear. It is thought to provide a link between the actin cytoskeleten and membrane associated proteins, playing a role in transduction of extracellular signals. It has been implicated in cell proliferation and cellular motility. Mutations in the NF2 gene cause neurofibromatosis type II, a condition characterised by the development of tumors in the central nervous system.Synonyms: Moesin-ezrin-radixin-like protein, NF2, Neurofibromin-2, SCH, Schwannomerlin, Schwannomerlin, Schwannomin, Schwannomin
    ID gène
    4771
    NCBI Accession
    NP_000259
    UniProt
    P35240
    Pathways
    Cell-Cell Junction Organization
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