MEF2A anticorps (pThr319)

N° du produit ABIN401543

Détail du produit anti-MEF2A anticorps

Antigène: MEF2A (Myocyte Enhancer Factor 2A (MEF2A))

Épitope: pThr319

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MEF2A est non-conjugé

Application: Immunofluorescence (IF)

Specificité: This antibody detects endogenous levels of MEF2A only when phosphorylated at Thr319.

Purification: Affinity Chromatography using epitope-specific phosphopeptide. The antibody against non-phosphopeptide was removed by chromatography using non-phosphopeptide corresponding to the phosphorylation site.

Immunogène: The antiserum was produced against synthesized phosphopeptide derived from Human MEF2A around the phosphorylation site of Thr319 (V-T-TP-P-S).

Information d'application

Indications d'application: Immunofluorescence: 1/100approx. 1/200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % Sodium Azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: -20 °C

Stockage commentaire: Store the antibody (in aliquots) at-20 °C.

Détails sur MEF2A

Antigène: MEF2A (Myocyte Enhancer Factor 2A (MEF2A))

Autre désignation: MEF2A (MEF2A Produits)

Synonymes: anticorps ADCAD1, anticorps RSRFC4, anticorps RSRFC9, anticorps mef2, anticorps A430079H05Rik, anticorps mef2a, anticorps wu:fd19d02, anticorps adcad1, anticorps rsrfc4, anticorps rsrfc9, anticorps sl2, anticorps MEF2A, anticorps xmef2a, anticorps myocyte enhancer factor 2A, anticorps myocyte enhancer factor 2aa, anticorps myocyte enhancer factor 2a, anticorps myocyte-specific enhancer factor 2A, anticorps myocyte-specific enhancer factor 2a, putative, anticorps myocyte enhancer factor 2A L homeolog, anticorps MEF2A, anticorps Mef2a, anticorps mef2aa, anticorps EDI_092490, anticorps EDI_038250, anticorps Smp_161530, anticorps mef2a.L, anticorps mef2a, anticorps LOC539054

Sujet: The myocyte enhancer factor-2 (MEF-2) family of transcription factors associated with co-repessors or co-activators to regulate development and function of T cells, neuronal cells and muscle cells. Four family members arise from alternatively spliced transcripts, termed MEF-2A, -2B, -2C and -2D. These members bind as homo- and heterodimers to the MEF-2 site in the promoter region of affected genes. Differential regulation in the expression of the four transcripts implies functional distinction for each during embryogenesis and development. The process of differentiation from mesodermal precursor cells to myoblasts has led to the discovery of a variety of tissue-specific factors that regulate muscle gene expression. The myogenic basic helix-loop-helix proteins, including MyoD, myogenin, Myf-5 and MRF-4, are one class of identified factors. A second family of DNA binding regulatory proteins is the myocyte-specific enhancer factor-2 (MEF-2) family. Each of these proteins binds to the MEF-2 target DNA sequence present in the regulatory regions of many muscle-specific genes.Synonyms: MEF2, Myocyte-specific enhancer factor 2A, Serum response factor-like protein 1

ID gène: 4205

NCBI Accession: NP_001124398

UniProt: Q02078

Pathways: Neurotrophin Signaling Pathway, Activation of Innate immune Response, Carbohydrate Homeostasis, Chromatin Binding, Regulation of Muscle Cell Differentiation, Toll-Like Receptors Cascades