Tel:
+49 (0)241 95 163 153
Fax:
+49 (0)241 95 163 155
E-Mail:
orders@anticorps-enligne.fr

ATF6B anticorps (Middle Region)

ATF6B Reactivité: Humain, Souris, Rat, Porc, Boeuf (Vache), Cheval, Chien WB Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN404752
  • Antigène Voir toutes ATF6B Anticorps
    ATF6B (Activating Transcription Factor 6 beta (ATF6B))
    Épitope
    • 15
    • 8
    • 7
    • 6
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Middle Region
    Reactivité
    • 33
    • 29
    • 9
    • 5
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    Humain, Souris, Rat, Porc, Boeuf (Vache), Cheval, Chien
    Hôte
    • 47
    • 1
    Lapin
    Clonalité
    • 47
    • 1
    Polyclonal
    Conjugué
    • 17
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp ATF6B est non-conjugé
    Application
    • 41
    • 23
    • 13
    • 13
    • 6
    • 4
    • 4
    • 3
    • 2
    • 1
    Western Blotting (WB)
    Séquence
    FNRTESLRLA DELSGWVQRH QRGRRKIPQR AQERQKSQPR KKSPPVKAVP
    Homologie
    Cow: 86%, Dog: 93%, Horse: 93%, Human: 100%, Mouse: 86%, Pig: 85%, Rat: 86%
    Attributs du produit
    This is a rabbit polyclonal antibody against CREBL1. It was validated on Western Blot using a cell lysate as a positive control.
    Purification
    Affinity Purified
    Immunogène
    The immunogen is a synthetic peptide directed towards the middle region of human CREBL1
    Top Product
    Discover our top product ATF6B Anticorps primaire
  • Indications d'application
    Optimal working dilutions should be determined experimentally by the investigator.
    Commentaires

    Antigen size: 703 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Conseil sur la manipulation
    Avoid repeated freeze-thaw cycles.
    Stock
    -20 °C
    Stockage commentaire
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Antigène
    ATF6B (Activating Transcription Factor 6 beta (ATF6B))
    Autre désignation
    CREBL1 (ATF6B Produits)
    Synonymes
    anticorps CREBL1, anticorps CREB-RP, anticorps G13, anticorps AA617266, anticorps ATF6beta, anticorps Creb-rp, anticorps Crebl1, anticorps activating transcription factor 6 beta, anticorps cyclic AMP-dependent transcription factor ATF-6 beta, anticorps ATF6B, anticorps LOC745411, anticorps Atf6b
    Sujet
    ATF6B(CREBL1) is a transcription factor in the unfolded protein response (UPR) pathway during ER stress. Either as a homodimer or as a heterodimer with ATF6-alpha, the protein binds to the ER stress response element, interacting with nuclear transcription factor Y to activate UPR target genes. ATF6B is normally found in the membrane of the endoplasmic reticulum, however, under ER stress, the N-terminal cytoplasmic domain is cleaved from the rest of the protein and translocates to the nucleus. Two transcript variants encoding different isoforms have been found for this gene.The protein encoded by this gene bears sequence similarity with the Creb/ATF subfamily of the bZip superfamily of transcription factors. It localizes to both the cytoplasm and the nucleus. The gene localizes to the major histocompatibility complex (MHC) class III region on chromosome 6. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
    Alias Symbols: CREB-RP, FLJ10066, G13, CREBL1
    Protein Interaction Partner: CREBZF, XBP1, ATF6B, CDK6, UBC, SUMO2, ATF6, NFYC, MBTPS1, PHOX2A, MBTPS2, NFYA, HCVgp1,
    Protein Size: 703
    Poids moléculaire
    77 kDa
    ID gène
    1388
    NCBI Accession
    NM_004381, NP_004372
    UniProt
    Q99941
    Pathways
    Thyroid Hormone Synthesis, Myometrial Relaxation and Contraction
Vous êtes ici:
Support technique