PARP11 anticorps (Middle Region)

N° du produit ABIN404898

Détail du produit anti-PARP11 anticorps

Antigène: PARP11 (Poly (ADP-Ribose) Polymerase Family, Member 11 (PARP11))

Épitope: Middle Region

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Chien, Cheval, Cobaye, Lapin

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PARP11 est non-conjugé

Application: Western Blotting (WB)

Séquence: IKHGNTFQIH GVSLQQRHLF RTYKSMFLAR VLIGDYINGD SKYMRPPSKD

Homologie: Cow: 93%, Dog: 93%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

Attributs du produit: This is a rabbit polyclonal antibody against PARP11. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of human PARP11

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 331 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur PARP11

Antigène: PARP11 (Poly (ADP-Ribose) Polymerase Family, Member 11 (PARP11))

Autre désignation: PARP11 (PARP11 Produits)

Synonymes: anticorps 5330431N24Rik, anticorps AI851877, anticorps ARTD11, anticorps HIN1L, anticorps C12orf6, anticorps parp11, anticorps MGC82612, anticorps PARP11, anticorps RGD1561791, anticorps poly (ADP-ribose) polymerase family, member 11, anticorps poly(ADP-ribose) polymerase family member 11, anticorps poly(ADP-ribose) polymerase family member 11 S homeolog, anticorps poly(ADP-ribose) polymerase family member 11 L homeolog, anticorps Parp11, anticorps PARP11, anticorps parp11.S, anticorps parp11.L, anticorps parp11

Sujet: PARP1 encodes a chromatin-associated enzyme, poly(ADP-ribosyl)transferase, which modifies various nuclear proteins by poly(ADP-ribosyl)ation. The modification is dependent on DNA and is involved in the regulation of various important cellular processes such as differentiation, proliferation, and tumor transformation and also in the regulation of the molecular events involved in the recovery of cell from DNA damage. In addition, this enzyme may be the site of mutation in Fanconi anemia, and may participate in the pathophysiology of type I diabetes. PARP1 can be cleaved resulting in fragements of 29 and 85 kDa.
Alias Symbols: C12orf6, DKFZp779H0122
Protein Interaction Partner: MDFI, TRIP13, DCAF11, RNF114, OTUD4, LYZ, GTPBP3, NUP98,
Protein Size: 331

Poids moléculaire: 39 kDa

ID gène: 57097

NCBI Accession: NM_020367, NP_065100

UniProt: Q9NR21