Kv2.1/KCNB1 anticorps (Middle Region)

N° du produit ABIN404910

Détail du produit anti-Kv2.1/KCNB1 anticorps

Antigène: Kv2.1/KCNB1 (KCNB1) (Potassium Voltage-Gated Channel, Shab-Related Subfamily, Member 1 (KCNB1))

Épitope: Middle Region

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Chien, Cheval, Porc, Cobaye

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Kv2.1/KCNB1 est non-conjugé

Application: Western Blotting (WB)

Séquence: YIDADTDDEG QLLYSVDSSP PKSLPGSTSP KFSTGTRSEK NHFESSPLPT

Homologie: Cow: 92%, Dog: 93%, Guinea Pig: 86%, Horse: 86%, Human: 100%, Mouse: 79%, Pig: 93%, Rat: 86%

Attributs du produit: This is a rabbit polyclonal antibody against KCNB1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of human KCNB1

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 858 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur Kv2.1/KCNB1

Antigène: Kv2.1/KCNB1 (KCNB1) (Potassium Voltage-Gated Channel, Shab-Related Subfamily, Member 1 (KCNB1))

Autre désignation: KCNB1 (KCNB1 Produits)

Synonymes: anticorps KCNB1, anticorps Kcnb1, anticorps Kcr1-1, anticorps Kv2.1, anticorps Shab, anticorps DRK1PC, anticorps DRK1, anticorps KV2.1, anticorps h-DRK1, anticorps potassium voltage-gated channel subfamily B member 1, anticorps potassium voltage-gated channel, Shab-related subfamily, member 1, anticorps potassium channel, voltage gated Shab related subfamily B, member 1, anticorps potassium voltage gated channel, Shab-related subfamily, member 1, anticorps KCNB1, anticorps kcnb1, anticorps LOC100541632, anticorps Kcnb1

Sujet: Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. Four sequence-related potassium channel genes - shaker, shaw, shab, and shal - have been identified in Drosophila, and each has been shown to have human homolog(s). This gene encodes a member of the potassium channel, voltage-gated, shab-related subfamily. This member is a delayed rectifier potassium channel and its activity is modulated by some other family members.Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. Four sequence-related potassium channel genes - shaker, shaw, shab, and shal - have been identified in Drosophila, and each has been shown to have human homolog(s). This gene encodes a member of the potassium channel, voltage-gated, shab-related subfamily. This member is a delayed rectifier potassium channel and its activity is modulated by some other family members. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: DRK1, KV2.1, h-DRK1
Protein Interaction Partner: STX1A, KCNG3, KCNG4, KCNV1, KCNB2, KCNG1, KCNB1, SRC, SUMO1, NEDD4L, KCNV2, KCNG2, KCNS3, PTPRE, SNAP25, KCNH1,
Protein Size: 858

Poids moléculaire: 96 kDa

ID gène: 3745

NCBI Accession: NM_004975, NP_004966

UniProt: Q14721

Pathways: Synaptic Membrane