TR4 anticorps (N-Term)

N° du produit ABIN405149

Détail du produit anti-TR4 anticorps

Antigène: TR4 (NR2C2) (Nuclear Receptor Subfamily 2, Group C, Member 2 (NR2C2))

Épitope: N-Term

Reactivité: Humain, Rat, Souris, Boeuf (Vache), Chien, Lapin, Cheval, Cobaye, Poisson zèbre (Danio rerio)

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TR4 est non-conjugé

Application: Western Blotting (WB)

Séquence: FTSLNKEKIV TDQQTGQKIQ IVTAVDASGS PKQQFILTSP DGAGTGKVIL

Homologie: Cow: 88%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 91%

Attributs du produit: This is a rabbit polyclonal antibody against NR2C2. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human NR2C2

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 615 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur TR4

Antigène: TR4 (NR2C2) (Nuclear Receptor Subfamily 2, Group C, Member 2 (NR2C2))

Autre désignation: NR2C2 (NR2C2 Produits)

Synonymes: anticorps TAK1, anticorps TR2R1, anticorps TR4, anticorps hTAK1, anticorps Tr4, anticorps gb:dq017625, anticorps im:6911408, anticorps mKIAA4145, anticorps nuclear receptor subfamily 2 group C member 2, anticorps nuclear receptor subfamily 2, group C, member 2, anticorps NR2C2, anticorps Nr2c2, anticorps nr2c2

Sujet: Members of the nuclear hormone receptor family, such as NR2C2, act as ligand-activated transcription factors. The proteins have an N-terminal transactivation domain, a central DNA-binding domain with 2 zinc fingers, and a ligand-binding domain at the C terminus. The activated receptor/ligand complex is translocated to the nucleus where it binds to hormone response elements of target genes. Members of the nuclear hormone receptor family, such as NR2C2, act as ligand-activated transcription factors. The proteins have an N-terminal transactivation domain, a central DNA-binding domain with 2 zinc fingers, and a ligand-binding domain at the C terminus. The activated receptor/ligand complex is translocated to the nucleus where it binds to hormone response elements of target genes (Yoshikawa et al., 1996 [PubMed 8661150]).[supplied by OMIM]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: TAK1, TR2R1, TR4, hTAK1
Protein Interaction Partner: VPRBP, CUL4B, UBC, DDB1, KDM1A, NR2C2, HSP90AA1, JAZF1, TAB2, TRAF6, PELI1, PELI2, RBCK1, PDLIM7, TAB1, TRIM28, MTA1, HDAC3, NR2C1, RBBP4, HDAC1, DNMT1, CHD4, Cebpb, ITSN2, CD2AP, RXRB, NR2C2AP, PEBP1, HSP90AB1, CDC37, IKBKB, FKBP5, TRAF2, CHUK, HNF4A, AR
Protein Size: 615

Poids moléculaire: 67 kDa

ID gène: 7182

NCBI Accession: NM_003298, NP_003289

UniProt: P49116

Pathways: TCR Signaling, Nuclear Receptor Transcription Pathway, Steroid Hormone Mediated Signaling Pathway, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Tube Formation, Toll-Like Receptors Cascades