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Cytokeratin 1 anticorps (Middle Region)

KRT1 Reactivité: Humain, Rat, Lapin, Chien WB, IHC Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN405458
  • Antigène Voir toutes Cytokeratin 1 (KRT1) Anticorps
    Cytokeratin 1 (KRT1) (Keratin 1 (KRT1))
    Épitope
    • 21
    • 16
    • 16
    • 5
    • 5
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Middle Region
    Reactivité
    • 97
    • 57
    • 43
    • 24
    • 16
    • 13
    • 9
    • 8
    • 7
    • 5
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Humain, Rat, Lapin, Chien
    Hôte
    • 77
    • 43
    • 1
    Lapin
    Clonalité
    • 70
    • 51
    Polyclonal
    Conjugué
    • 50
    • 15
    • 10
    • 7
    • 5
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    Cet anticorp Cytokeratin 1 est non-conjugé
    Application
    • 82
    • 55
    • 33
    • 30
    • 27
    • 27
    • 26
    • 19
    • 17
    • 14
    • 13
    • 8
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    Séquence
    GSYGSGSSSG GYRGGSGGGG GGSSGGRGSG GGSSGGSIGG RGSSSGGVKS
    Homologie
    Dog: 86%, Human: 100%, Rabbit: 93%, Rat: 93%
    Attributs du produit
    This is a rabbit polyclonal antibody against KRT1. It was validated on Western Blot using a cell lysate as a positive control.
    Purification
    Affinity Purified
    Immunogène
    The immunogen is a synthetic peptide directed towards the middle region of human KRT1
    Top Product
    Discover our top product KRT1 Anticorps primaire
  • Indications d'application
    Optimal working dilutions should be determined experimentally by the investigator.
    Commentaires

    Antigen size: 644 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Conseil sur la manipulation
    Avoid repeated freeze-thaw cycles.
    Stock
    -20 °C
    Stockage commentaire
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Antigène
    Cytokeratin 1 (KRT1) (Keratin 1 (KRT1))
    Autre désignation
    KRT1 (KRT1 Produits)
    Synonymes
    anticorps CK1, anticorps EHK, anticorps EHK1, anticorps EPPK, anticorps K1, anticorps KRT1A, anticorps NEPPK, anticorps Krt-2.1, anticorps Krt2-1, anticorps Krt86, anticorps KRT1, anticorps Kb1, anticorps KER1, anticorps CK-1, anticorps Keratin-1, anticorps keratin 1, anticorps KRT1, anticorps Krt1
    Sujet
    KRT1 is a member of the keratin gene family. The type II cytokeratins consist of basic or neutral proteins which are arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues. This type II cytokeratin is specifically expressed in the spinous and granular layers of the epidermis with family member KRT10 and mutations in these genes have been associated with bullous congenital ichthyosiform erythroderma.The protein encoded by this gene is a member of the keratin gene family. The type II cytokeratins consist of basic or neutral proteins which are arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues. This type II cytokeratin is specifically expressed in the spinous and granular layers of the epidermis with family member KRT10 and mutations in these genes have been associated with bullous congenital ichthyosiform erythroderma. The type II cytokeratins are clustered in a region of chromosome 12q12-q13. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
    Alias Symbols: CK1, EHK1, K1, KRT1A, EHK, EPPK, NEPPK
    Protein Interaction Partner: MDM2, LGR4, EED, ESR1, ADRB2, PAN2, Iqcb1, Nphp4, Cep290, Nphp1, Invs, GRDX, VCAM1, UBC, ITGA4, FN1, CDH1, APOA1, ALB, MAGOH, EIF4A3, KRT10, KRT9, KRT2, SLC25A5, SHC1, PIK3R2, INPPL1, GRB2, EPS15, CRK, AP2M1, CBL, UBASH3B, NEDD8, CAND1, DCUN1D1, COPS5, CO
    Protein Size: 644
    Poids moléculaire
    66 kDa
    ID gène
    3848
    NCBI Accession
    NM_006121, NP_006112
    UniProt
    P04264
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