ATG4A anticorps (N-Term)

N° du produit ABIN405496

Détail du produit anti-ATG4A anticorps

Antigène: ATG4A (Autophagy related 4A Cysteine Peptidase (ATG4A))

Épitope: N-Term

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Chien, Cheval, Porc, Lapin, Poisson zèbre (Danio rerio)

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ATG4A est non-conjugé

Application: Western Blotting (WB)

Séquence: DAGWGCMLRC GQMMLAQALI CRHLGRDWSW EKQKEQPKEY QRILQCFLDR

Homologie: Cow: 100%, Dog: 93%, Horse: 100%, Human: 100%, Mouse: 93%, Pig: 100%, Rabbit: 100%, Rat: 93%, Zebrafish: 79%

Attributs du produit: This is a rabbit polyclonal antibody against ATG4A. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human ATG4A

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 398 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur ATG4A

Antigène: ATG4A (Autophagy related 4A Cysteine Peptidase (ATG4A))

Autre désignation: ATG4A (ATG4A Produits)

Synonymes: anticorps apg4a, anticorps autl2, anticorps F6E13.27, anticorps APG4A, anticorps zgc:111958, anticorps Aut2a, anticorps AUTL2, anticorps AI627006, anticorps AV169859, anticorps Apg4a, anticorps Atg4al, anticorps Autl2, anticorps Atg4a, anticorps autophagy related 4A cysteine peptidase L homeolog, anticorps autophagy related 4A cysteine peptidase, anticorps Peptidase family C54 protein, anticorps ATG4 autophagy related 4 homolog A (S. cerevisiae), anticorps autophagy related 4A, cysteine peptidase, anticorps atg4a.L, anticorps ATG4A, anticorps AT2G44140, anticorps atg4a, anticorps Atg4a

Sujet: Autophagy is the process by which endogenous proteins and damaged organelles are destroyed intracellularly. Autophagy is postulated to be essential for cell homeostasis and cell remodeling during differentiation, metamorphosis, non-apoptotic cell death, and aging. Reduced levels of autophagy have been described in some malignant tumors, and a role for autophagy in controlling the unregulated cell growth linked to cancer has been proposed. ATG4A is a member of the autophagin protein family. ATG4A is also designated as a member of the C-54 family of cysteine proteases.Autophagy is the process by which endogenous proteins and damaged organelles are destroyed intracellularly. Autophagy is postulated to be essential for cell homeostasis and cell remodeling during differentiation, metamorphosis, non-apoptotic cell death, and aging. Reduced levels of autophagy have been described in some malignant tumors, and a role for autophagy in controlling the unregulated cell growth linked to cancer has been proposed. This gene encodes a member of the autophagin protein family. The encoded protein is also designated as a member of the C-54 family of cysteine proteases. Transcript variants that encode distinct isoforms have been identified.
Alias Symbols: APG4A, AUTL2
Protein Interaction Partner: CDKL3, GABARAPL1, GABARAPL2, ATG101, MAP1LC3B,
Protein Size: 398

Poids moléculaire: 45 kDa

ID gène: 115201

NCBI Accession: NM_052936, NP_443168

UniProt: Q8WYN0

Pathways: Autophagy