UBE2D3 anticorps (N-Term)

N° du produit ABIN405515

Détail du produit anti-UBE2D3 anticorps

Antigène: UBE2D3 (Ubiquitin-Conjugating Enzyme E2D 3 (UBE2D3))

Épitope: N-Term

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Chien, Cobaye, Cheval, Lapin, Saccharomyces cerevisiae, Poisson zèbre (Danio rerio)

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp UBE2D3 est non-conjugé

Application: Western Blotting (WB)

Séquence: MALKRINKEL SDLARDPPAQ CSAGPVGDDM FHWQATIMGP NDSPYQGGVF

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 92%, Rat: 100%, Yeast: 92%, Zebrafish: 92%

Attributs du produit: This is a rabbit polyclonal antibody against UBE2D3. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human UBE2D3

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 147 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur UBE2D3

Antigène: UBE2D3 (Ubiquitin-Conjugating Enzyme E2D 3 (UBE2D3))

Autre désignation: UBE2D3 (UBE2D3 Produits)

Synonymes: anticorps E2(17)KB3, anticorps UBC4/5, anticorps UBCH5C, anticorps eff, anticorps fb36f02, anticorps wu:fb36f02, anticorps zgc:56340, anticorps 1100001F19Rik, anticorps 9430029A22Rik, anticorps AA414951, anticorps UBE2D3P, anticorps Xubc4, anticorps e2(17)kb3, anticorps ubc4/5, anticorps ubch5c, anticorps ube2d3.1, anticorps ube2d2, anticorps xubc4, anticorps wu:fj13d01, anticorps zgc:73200, anticorps ubiquitin conjugating enzyme E2 D3, anticorps ubiquitin-conjugating enzyme E2D 3, anticorps ubiquitin conjugating enzyme E2 D3 L homeolog, anticorps ubiquitin-conjugating enzyme E2D 2 (UBC4/5 homolog, yeast), like, anticorps UBE2D3, anticorps ube2d3, anticorps Ube2d3, anticorps LOC100223566, anticorps ube2d3.L, anticorps ube2d2l

Sujet: The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. UBE2D3 is a member of the E2 ubiquitin-conjugating enzyme family. This enzyme functions in the ubiquitination of the tumor-suppressor protein p53, which is induced by an E3 ubiquitin-protein ligase.The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. This enzyme functions in the ubiquitination of the tumor-suppressor protein p53, which is induced by an E3 ubiquitin-protein ligase. Multiple spliced transcript variants have been found for this gene, but the full-length nature of some variants has not been determined.
Alias Symbols: E2(17)KB3, MGC43926, MGC5416, UBC4/5, UBCH5C
Protein Interaction Partner: NHLRC1, DTX2, TRIM63, RNF146, RNF26, RBX1, UBC, RNF5, RNF2, NEDD4, MID1, STUB1, TRIM39, OTUB1, MDM2, RNF111, TRIM33, PRPF19, RNF115, TRIM58, BTRC, MARCH7, NFKBIA, ARIH1, FBXW11, UBE2D3, PARK2, BRCA1, BARD1, UBE3A, MSL1, UBA1, CBLC, SMURF1, RNF130, UBA6, M
Protein Size: 147

Poids moléculaire: 17 kDa

ID gène: 7323

NCBI Accession: NM_003340, NP_003331

UniProt: P61077

Pathways: Activation of Innate immune Response, Toll-Like Receptors Cascades