MARCH1 anticorps (N-Term)

N° du produit ABIN405536

Détail du produit anti-MARCH1 anticorps

Antigène: MARCH1 (Membrane-Associated Ring Finger (C3HC4) 1, E3 Ubiquitin Protein Ligase (MARCH1))

Épitope: N-Term

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Cheval, Lapin, Cobaye, Chien

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MARCH1 est non-conjugé

Application: Western Blotting (WB)

Séquence: LQASSPTTGT APRSQSRLSV CPSTQDICRI CHCEGDEESP LITPCRCTGT

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

Attributs du produit: This is a rabbit polyclonal antibody against MARCH1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human MARCH1

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 272 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur MARCH1

Antigène: MARCH1 (Membrane-Associated Ring Finger (C3HC4) 1, E3 Ubiquitin Protein Ligase (MARCH1))

Autre désignation: MARCH1 (MARCH1 Produits)

Synonymes: anticorps MARCH-I, anticorps RNF171, anticorps 2900024D24Rik, anticorps BB085186, anticorps RGD1305148, anticorps MARCH1, anticorps DKFZp459K1250, anticorps membrane associated ring-CH-type finger 1, anticorps membrane-associated ring finger (C3HC4) 1, anticorps MARCH1, anticorps March1

Sujet: MARCH1 is an E3 ubiquitin-protein ligase that may mediate ubiquitination of TFRC, CD86 and FAS, and promote their subsequent endocytosis and sorting to lysosomes via multivesicular bodies. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfer the ubiquitin to targeted substrates.
Alias Symbols: DKFZp564M1682, FLJ20668, MARCH-I, RNF171
Protein Interaction Partner: TNFRSF10A, UBE2H, UBE2D1, CDC34, TFRC, UBC, HLA-DRB1, HLA-DRA, PPP2R1B, PPP2R1A, CD86,
Protein Size: 272

Poids moléculaire: 31 kDa

ID gène: 55016

NCBI Accession: NM_017923, NP_060393