MARCH4 anticorps (N-Term)

N° du produit ABIN405545

Détail du produit anti-MARCH4 anticorps

Antigène: MARCH4 (Membrane-Associated Ring Finger (C3HC4) 4, E3 Ubiquitin Protein Ligase (MARCH4))

Épitope: N-Term

Reactivité: Humain, Souris, Rat, Chien, Cheval, Cobaye, Lapin

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MARCH4 est non-conjugé

Application: Western Blotting (WB)

Séquence: GLLKCRCRML FNDLKVFLLR RPPQAPLPMH GDPQPPGLAA NNTLPALGAG

Homologie: Dog: 92%, Guinea Pig: 92%, Horse: 100%, Human: 100%, Mouse: 85%, Rabbit: 85%, Rat: 92%

Attributs du produit: This is a rabbit polyclonal antibody against MARCH4. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human MARCH4

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 410 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur MARCH4

Antigène: MARCH4 (Membrane-Associated Ring Finger (C3HC4) 4, E3 Ubiquitin Protein Ligase (MARCH4))

Autre désignation: MARCH4 (MARCH4 Produits)

Synonymes: anticorps MARCH-IV, anticorps RNF174, anticorps BC056494, anticorps mKIAA1399, anticorps MARCH4, anticorps si:ch211-239d11.2, anticorps membrane associated ring-CH-type finger 4, anticorps membrane-associated ring finger (C3HC4) 4, anticorps MARCH4, anticorps March4, anticorps march4

Sujet: MARCH4 is an E3 ubiquitin-protein ligase that may mediate ubiquitination of MHC-I and CD4, and promote their subsequent endocytosis and sorting to lysosomes via multivesicular bodies. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfer the ubiquitin to targeted substrates.
Alias Symbols: MARCH-IV, MGC104908, RNF174
Protein Interaction Partner: UBE2H, UBE2D1, ULBP1, CD4,
Protein Size: 410

Poids moléculaire: 45 kDa

ID gène: 57574

NCBI Accession: NM_020814, NP_065865

UniProt: Q9P2E8