SKAP1 anticorps (N-Term)

N° du produit ABIN405786

Détail du produit anti-SKAP1 anticorps

Antigène: SKAP1 (Src Kinase Associated phosphoprotein 1 (SKAP1))

Épitope: N-Term

Reactivité: Humain, Rat, Souris, Lapin

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SKAP1 est non-conjugé

Application: Western Blotting (WB)

Séquence: RDHILRGFQQ IKARYYWDFQ PQGGDIGQDS SDDNHSGTLG LSLTSDAPFL

Homologie: Human: 100%, Mouse: 86%, Rabbit: 86%, Rat: 79%

Attributs du produit: This is a rabbit polyclonal antibody against SKAP1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human SKAP1

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 359 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur SKAP1

Antigène: SKAP1 (Src Kinase Associated phosphoprotein 1 (SKAP1))

Autre désignation: SKAP1 (SKAP1 Produits)

Synonymes: anticorps 1700091G21Rik, anticorps Scap1, anticorps Skap-55, anticorps SCAP1, anticorps SKAP55, anticorps Skap55, anticorps src family associated phosphoprotein 1, anticorps src kinase associated phosphoprotein 1, anticorps Skap1, anticorps SKAP1

Sujet: SKAP1 Is a T cell adaptor protein, a class of intracellular molecules with modular domains capable of recruiting additional proteins but that exhibit no intrinsic enzymatic activity. The encoded protein contains a unique N-terminal region followed by a PH domain and C-terminal SH3 domain. Along with the adhesion and degranulation-promoting adaptor protein, the encoded protein plays a critical role in inside-out signaling by coupling T-cell antigen receptor stimulation to the activation of integrins. This gene encodes a T cell adaptor protein, a class of intracellular molecules with modular domains capable of recruiting additional proteins but that exhibit no intrinsic enzymatic activity. The encoded protein contains a unique N-terminal region followed by a PH domain and C-terminal SH3 domain. Along with the adhesion and degranulation-promoting adaptor protein, the encoded protein plays a critical role in inside-out signaling by coupling T-cell antigen receptor stimulation to the activation of integrins.
Alias Symbols: SCAP1, SKAP55
Protein Interaction Partner: FAM102A, PRAM1, SH2D4A, BLCAP, APP, LCK, FYN, FYB, SRC, LYN, PTPRC, GRB2, SKAP1,
Protein Size: 359

Poids moléculaire: 41 kDa

ID gène: 8631

NCBI Accession: NM_003726, NP_003717

UniProt: Q86WV1