SPTLC2 anticorps (N-Term)

N° du produit ABIN406006

Détail du produit anti-SPTLC2 anticorps

Antigène: SPTLC2 (serine Palmitoyltransferase, Long Chain Base Subunit 2 (SPTLC2))

Épitope: N-Term

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Chien, Cobaye, Lapin, Poisson zèbre (Danio rerio), Cheval

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SPTLC2 est non-conjugé

Application: Western Blotting (WB)

Séquence: VLTYVGYGVL TLFGYLRDFL RYWRIEKCHH ATEREEQKDF VSLYQDFENF

Homologie: Cow: 100%, Dog: 91%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%

Attributs du produit: This is a rabbit polyclonal antibody against SPTLC2. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human SPTLC2

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 562 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur SPTLC2

Antigène: SPTLC2 (serine Palmitoyltransferase, Long Chain Base Subunit 2 (SPTLC2))

Autre désignation: SPTLC2 (SPTLC2 Produits)

Synonymes: anticorps HSN1C, anticorps LCB2, anticorps LCB2A, anticorps NSAN1C, anticorps SPT2, anticorps hLCB2a, anticorps sptlc2, anticorps zgc:110661, anticorps AI173915, anticorps mKIAA0526, anticorps Pomt2, anticorps LCB2a, anticorps SPTLC2, anticorps serine palmitoyltransferase long chain base subunit 2, anticorps serine palmitoyltransferase 2, anticorps serine palmitoyltransferase, long chain base subunit 2 S homeolog, anticorps serine palmitoyltransferase, long chain base subunit 2a, anticorps serine palmitoyltransferase, long chain base subunit 2, anticorps SPTLC2, anticorps LOC100446763, anticorps sptlc2, anticorps sptlc2.S, anticorps sptlc2a, anticorps Sptlc2

Sujet: SPTLC2 is a long chain base subunit of serine palmitoyltransferase. Serine palmitoyltransferase, which consists of two different subunits, is the key enzyme in sphingolipid biosynthesis. It catalyzes the pyridoxal-5-prime-phosphate-dependent condensation of L-serine and palmitoyl-CoA to 3-oxosphinganine. Mutations in this gene were identified in patients with hereditary sensory neuropathy type I.This gene encodes a long chain base subunit of serine palmitoyltransferase. Serine palmitoyltransferase, which consists of two different subunits, is the key enzyme in sphingolipid biosynthesis. It catalyzes the pyridoxal-5-prime-phosphate-dependent condensation of L-serine and palmitoyl-CoA to 3-oxosphinganine. Mutations in this gene were identified in patients with hereditary sensory neuropathy type I. Alternatively spliced variants encoding different isoforms have been identified. PRIMARYREFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP 1-973 AB011098.1 1-973 974-1108 BQ338973.1 306-440 1109-3679 AB011098.1 1109-3679 3680-4578 AB011098.1 3682-4580 4579-4876 BG024616.1 326-623 4877-6812 AB011098.1 4879-6814 6813-7189 W24363.1 55-431 7190-7250 BM992457.1 1-61 c
Alias Symbols: KIAA0526, LCB2, SPT2, HSN1C, LCB2A, NSAN1C, hLCB2a
Protein Interaction Partner: UBC, BCL6, SPTLC1,
Protein Size: 562

Poids moléculaire: 63 kDa

ID gène: 9517

NCBI Accession: NM_004863, NP_004854

UniProt: O15270