ITPK1 anticorps (N-Term)

N° du produit ABIN406459

Détail du produit anti-ITPK1 anticorps

Antigène: ITPK1 (Inositol-Tetrakisphosphate 1-Kinase (ITPK1))

Épitope: N-Term

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Lapin, Chien, Cobaye, Cheval, Poisson zèbre (Danio rerio)

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ITPK1 est non-conjugé

Application: Western Blotting (WB)

Séquence: MEVVQLNLSR PIEEQGPLDV IIHKLTDVIL EADQNDSQSL ELVHRFQEYI

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 79%

Attributs du produit: This is a rabbit polyclonal antibody against ITPK1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human ITPK1

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 414 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur ITPK1

Antigène: ITPK1 (Inositol-Tetrakisphosphate 1-Kinase (ITPK1))

Autre désignation: ITPK1 (ITPK1 Produits)

Synonymes: anticorps ITRPK1, anticorps BC031182, anticorps wu:fj15d08, anticorps zgc:56075, anticorps inositol-tetrakisphosphate 1-kinase, anticorps inositol 1,3,4-triphosphate 5/6 kinase, anticorps inositol-tetrakisphosphate 1-kinase L homeolog, anticorps inositol-tetrakisphosphate 1-kinase a, anticorps ITPK1, anticorps Itpk1, anticorps itpk1.L, anticorps itpk1a

Sujet: ITPK1 is the kinase that can phosphorylate various inositol polyphosphate such as Ins(3,4,5,6)P4 or Ins(1,3,4)P3. It may also act as an isomerase that interconverts the inositol tetraphosphate isomers Ins(1,3,4,5)P4 and Ins(1,3,4,6)P4 in the presence of ADP and magnesium. It probably acts as the rate-limiting enzyme of the InsP6 pathway. ITPK1 modifies TNF-alpha-induced apoptosis by interfering with the activation of TNFRSF1A-associated death domain.
Alias Symbols: ITRPK1
Protein Interaction Partner: UBC, TP53, NFKBIA, JUN, ITPK1, GPS1, COPS8, TRAF2,
Protein Size: 414

Poids moléculaire: 45 kDa

ID gène: 3705

NCBI Accession: NM_014216, NP_055031

UniProt: Q13572