CD11c anticorps (PE)

N° du produit ABIN4369566

Détail du produit anti-CD11c anticorps (PE)

Antigène: CD11c (ITGAX) (Integrin, alpha X (Complement Component 3 Receptor 4 Subunit) (ITGAX))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp CD11c est conjugé à/à la PE

Application: Flow Cytometry (FACS), Immunoprecipitation (IP), Immunohistochemistry (Frozen Sections) (IHC (fro))

Fonction: Mouse monoclonal antibody raised against native ITGAX.

Specificité: This antibody reacts with ITGAX, a 150 KDa integrin expressed mainly on dendritic cells and tissue macrophages.

Réactivité croisée: Chien, Humain, Singe

Immunogène: Native purified ITGAX from human dendritic cells of synovial fluid.

Clone: BU15

Isotype: IgG1

Information d'application

Indications d'application: Flow Cytometry (20 µL in human blood cells 100 µL in whole blood or 10⁶ cells in a suspension)
The optimal working dilution should be determined by the end user.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: In PBS (0.2 % BSA, 0.09 % sodium azide)

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: Store in the dark at 4°C. Do not freeze.
Avoid prolonged exposure to light.
Aliquot to avoid repeated freezing and thawing.

Références pour anticorps anti-CD11c (PE) (ABIN4369566)

Sadhu, Hendrickson, Dick, Potter, Staunton: "Novel tools for functional analysis of CD11c: activation-specific, activation-independent, and activating antibodies." dans: Journal of immunoassay & immunochemistry, Vol. 29, Issue 1, pp. 42-57, (2007) (PubMed).

Myou, Zhu, Boetticher, Qin, Myo, Meliton, Lambertino, Munoz, Hamann, Leff: "Regulation of adhesion of AML14.3D10 cells by surface clustering of beta2-integrin caused by ERK-independent activation of cPLA2." dans: Immunology, Vol. 107, Issue 1, pp. 77-85, (2002) (PubMed).

Rezzonico, Imbert, Chicheportiche, Dayer et al.: "Ligation of CD11b and CD11c beta(2) integrins by antibodies or soluble CD23 induces macrophage inflammatory protein 1alpha (MIP-1alpha) and MIP-1beta production in primary human monocytes through a ..." dans: Blood, Vol. 97, Issue 10, pp. 2932-40, (2001) (PubMed).

Détails sur CD11c

Antigène: CD11c (ITGAX) (Integrin, alpha X (Complement Component 3 Receptor 4 Subunit) (ITGAX))

Autre désignation: CD11c / ITGAX (ITGAX Produits)

Synonymes: anticorps CD11C, anticorps SLEB6, anticorps RGD1561123, anticorps AI449405, anticorps Cd11c, anticorps Cr4, anticorps N418, anticorps integrin subunit alpha X, anticorps integrin alpha X, anticorps ITGAX, anticorps Itgax

ID gène: 3687

Pathways: Système du Complément, Activated T Cell Proliferation, Integrin Complex