FMR1 anticorps (Internal Region)

N° du produit ABIN452426

Détail du produit anti-FMR1 anticorps

Antigène: FMR1 (Fragile X Mental Retardation 1 (FMR1))

Épitope: AA 116-130, Internal Region

Reactivité: Humain, Rat

Hôte: Chèvre

Clonalité: Polyclonal

Conjugué: Cet anticorp FMR1 est non-conjugé

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Séquence: c-NPNKPATKDT FHKIK

Specificité: This antibody Recognizes FMR1.

Réactivité croisée (Details): Species reactivity (expected):Rat.
Species reactivity (tested):Human.

Purification: Ammonium Sulphate Precipitation followed by antigen Affinity Chromatography using the immunizing peptide.

Immunogène: Peptide with sequence from the internal region of the protein sequence according to NP_002015.1. Genename: FMR1

Information d'application

Indications d'application: Peptide ELISA: 1/32000. Western blot: Approx 70Da band observed in lysates of cell lines HeLa and Jurkat(calculated MW of 71.2 kDa according to NP_002015.1). Recommended concentration: 0.3 -1 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 0.5 mg/mL

Buffer: Tris saline, pH 7.3 containing 0.02 % Sodium Azide as preservative and 0.5 % BSA as stabilizer.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.

Détails sur FMR1

Antigène: FMR1 (Fragile X Mental Retardation 1 (FMR1))

Autre désignation: FMR1 / FMRP (FMR1 Produits)

Synonymes: anticorps AT24755, anticorps BcDNA:GM08679, anticorps CG6203, anticorps Dmel\\CG6203, anticorps EP(3)3517, anticorps FMR, anticorps FMR1, anticorps FMRP, anticorps FMRp, anticorps FXR, anticorps Fmrp, anticorps cg6203, anticorps dFMR, anticorps dFMR1, anticorps dFMRP, anticorps dFXR, anticorps dFXR1, anticorps dFXRP, anticorps dFmr1, anticorps dFmrp, anticorps dfmr, anticorps dfmr1, anticorps dfxr, anticorps dfxr1, anticorps dmfr1, anticorps fmr, anticorps fmr1, anticorps FRAXA, anticorps POF, anticorps POF1, anticorps zFMR1, anticorps Fmr-1, anticorps CG6203 gene product from transcript CG6203-RC, anticorps fragile X mental retardation 1, anticorps fragile X mental retardation syndrome 1, anticorps Fmr1, anticorps FMR1, anticorps fmr1

Sujet: FMRP is a RNA-binding protein that is associated to polysomes and may be involved in the transport of mRNA from the nucleus to the cytoplasm. Defects in FMR1 are the cause of Fragile X syndrome, which is a common genetic disease characterized by moderate to severe mental retardation, macroorchidism, large ears, prominent jaw, and high-pitched, jocular speech. The defect in most fragile X syndrome patients results from an amplification of a CGG repeat region which is directly in front of the coding region.Synonyms: Fragile X mental retardation 1 protein, Protein FMR-1

ID gène: 2332

NCBI Accession: NP_002015

UniProt: Q06787

Pathways: Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development