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Importin 11 anticorps (N-Term)

IPO11 Reactivité: Humain WB, EIA Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN453706
  • Antigène Voir toutes Importin 11 (IPO11) Anticorps
    Importin 11 (IPO11)
    Épitope
    • 10
    • 9
    • 8
    • 7
    • 7
    • 5
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    Reactivité
    • 47
    • 6
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Humain
    Hôte
    • 47
    Lapin
    Clonalité
    • 46
    Polyclonal
    Conjugué
    • 23
    • 6
    • 5
    • 5
    • 4
    • 4
    Cet anticorp Importin 11 est non-conjugé
    Application
    • 41
    • 32
    • 6
    • 3
    • 3
    • 2
    • 1
    Western Blotting (WB), Enzyme Immunoassay (EIA)
    Specificité
    This antibody reacts to IPO11.
    Purification
    Affinity chromatography on Protein A
    Immunogène
    KLH conjugated synthetic peptide selected from the N-term region of human IPO11
    Top Product
    Discover our top product IPO11 Anticorps primaire
  • Indications d'application
    ELISA: 1/1,000. Western blotting: 1/100 - 1/500.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.25 mg/mL
    Buffer
    PBS with 0.09 % (W/V) sodium azide
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Conseil sur la manipulation
    Avoid repeated freezing and thawing.
    Stock
    4 °C/-20 °C
    Stockage commentaire
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • Antigène
    Importin 11 (IPO11)
    Autre désignation
    RanBP11 / Importin-11 (IPO11 Produits)
    Synonymes
    anticorps MGC83107, anticorps IPO11, anticorps slrn, anticorps ranbp11, anticorps RanBP11, anticorps 1700081H05Rik, anticorps 2510001A17Rik, anticorps AI314624, anticorps AW555235, anticorps E330021B14Rik, anticorps Ranbp11, anticorps importin 11 S homeolog, anticorps importin 11, anticorps importin-11, anticorps ipo11.S, anticorps ipo11, anticorps IPO11, anticorps AFUA_1G03590, anticorps BDBG_04626, anticorps LOC100162908, anticorps Ipo11
    Sujet
    IPO11 functions in nuclear protein import as nuclear transport receptor. It serves as receptor for nuclear localization signals (NLS) in cargo substrates and is thought to mediate docking of the importin/substrate complex to the nuclear pore complex (NPC) through binding to nucleoporin and the complex is subsequently translocated through the pore by an energy requiring, Ran-dependent mechanism. At the nucleoplasmic side of the NPC, Ran binds to the importin, the importin/substrate complex dissociates and importin is re-exported from the nucleus to the cytoplasm where GTP hydrolysis releases Ran. The directionality of nuclear import is thought to be conferred by an asymmetric distribution of the GTP-and GDP-bound forms of Ran between the cytoplasm and nucleus (By similarity). It mediates the nuclear import of UBE2E3, and of RPL12 (By similarity).Synonyms: IPO11, Imp11, Ran-binding protein 11
    ID gène
    51194
    NCBI Accession
    NP_057422
    UniProt
    Q9UI26
    Pathways
    Protein targeting to Nucleus
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