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CCL2 anticorps (HRP)

CCL2 Reactivité: Humain EIA Hôte: Souris Monoclonal S101 HRP
N° du produit ABIN453918
  • Antigène Voir toutes CCL2 Anticorps
    CCL2 (Chemokine (C-C Motif) Ligand 2 (CCL2))
    Reactivité
    • 104
    • 66
    • 63
    • 18
    • 18
    • 18
    • 16
    • 9
    • 3
    • 3
    • 2
    • 1
    • 1
    Humain
    Hôte
    • 119
    • 61
    • 8
    • 7
    • 5
    • 3
    • 2
    • 2
    Souris
    Clonalité
    • 135
    • 72
    Monoclonal
    Conjugué
    • 114
    • 39
    • 14
    • 6
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    Cet anticorp CCL2 est conjugé à/à la HRP
    Application
    • 141
    • 75
    • 57
    • 29
    • 28
    • 25
    • 24
    • 17
    • 16
    • 15
    • 14
    • 13
    • 13
    • 13
    • 11
    • 6
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Enzyme Immunoassay (EIA)
    Specificité
    This monoclonal antibody reacts with natural and recombinant Human MCP-1. Does not react with Human interleukin-8 (IL-8) and other human cytokines tested such as interleukin-1 beta (IL1 beta), serum amyloid A (SAA) and epidermal growth factor (EGF)
    Réactivité croisée (Details)
    Species reactivity (tested):Human.
    Purification
    Affinity Chromatography on Protein G
    Immunogène
    Purified recombinant Human MCP1.
    Clone
    S101
    Isotype
    IgG1
    Top Product
    Discover our top product CCL2 Anticorps primaire
  • Indications d'application
    ELISA: This MCP1 antibody HRP-conjugated can be used as a Tracer/Detection antibody inSandwich ELISA applications for Human MCP-1 detection in combination with a Captureantibody (Cat#DM2032)Suggested Capture Coating Dose: approx. 0.3 μg/mLSubstrate: TMB. If the above suggested conditions are followed approximately 1.5 pg/mL ofMCP-1 in serum/plasma or 4 pg/mL of MCP-1 in medium can be detected with an assayrange of 0-1600 pg/mL.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    0.01 M PBS, pH 7.0 ± 0.1 in 50 % Glycerol and 0.01 % Thimerosal as a bacteriostat
    Agent conservateur
    Thimerosal (Merthiolate)
    Précaution d'utilisation
    This product contains thimerosal (merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Conseil sur la manipulation
    Avoid repeated freezing and thawing.
    Stock
    -20 °C
  • Antigène
    CCL2 (Chemokine (C-C Motif) Ligand 2 (CCL2))
    Autre désignation
    MCP1 / CCL2 (CCL2 Produits)
    Synonymes
    anticorps GDCF-2, anticorps HC11, anticorps HSMCR30, anticorps MCAF, anticorps MCP-1, anticorps MCP1, anticorps SCYA2, anticorps SMC-CF, anticorps AI323594, anticorps JE, anticorps Scya2, anticorps Sigje, anticorps MCP-1A, anticorps MCP1A, anticorps C-C motif chemokine ligand 2, anticorps chemokine (C-C motif) ligand 2, anticorps C-C motif chemokine 2, anticorps CCL2, anticorps Ccl2, anticorps LOC101120093
    Sujet
    Monocyte chemotactic protein-1 (MCP-1), also known as CCL2, monocyte chemotactic activating factor (MCAF) or glioma-derived chemotactic factor-2 (GDCF-2), is the product of the human JE gene and a member of the family of C-C (or beta) chemokines (1-4). The predicted molecular weight of MCP-1 protein is 11-13 kDa, but it may migrate at 20-30 kDa due to glycosylation. MCP-1 is secreted by a variety of cell types in response to pro-inflammatory stimuli and was originally described for its chemotactic activity on monocytes. This activity has led to studies demonstrating its role in diseases characterized by monocyte infiltrates such as psoriasis (5), rheumatoid arthritis (6) and atherosclerosis (7). MCP-1 may also contribute to tumor progression and angiogenesis (8). Signaling by MCP-1 is mediated by the G-protein coupled receptor CCR2 (9).Synonyms: C-C motif chemokine 2, HC-11, HC11, MCAF, MCP-1, Monocyte chemoattractant protein 1, Monocyte chemotactic and activating factor, Monocyte chemotactic protein 1, Monocyte secretory protein JE, SCYA2, Small-inducible cytokine A2
    ID gène
    6347
    NCBI Accession
    NP_002973
    UniProt
    P13500
    Pathways
    Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Immune Effector Process, ER-Nucleus Signaling, Unfolded Protein Response, Phosphorylation & l'infection par le SRAS-CoV-2
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