PER3 anticorps

N° du produit ABIN498324

Détail du produit anti-PER3 anticorps

Antigène: PER3 (Period Homolog 3 (PER3))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PER3 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Specificité: This antibody detects endogenous levels of Per3 protein. (region surrounding Pro2)

Réactivité croisée (Details): Species reactivity (tested):Human.

Purification: Affinity Chromatography using epitope-specific immunogen.

Information d'application

Indications d'application: Western blot 1/500-1/1000. Immunohistochemistry on Paraffin Sections: 1/50-1/200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: Phosphate buffered saline (PBS), pH ~7.2, 0.05 % Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur PER3

Antigène: PER3 (Period Homolog 3 (PER3))

Autre désignation: PER3 (PER3 Produits)

Synonymes: anticorps period3, anticorps rper3, anticorps GIG13, anticorps 2810049O06Rik, anticorps mPer3, anticorps period circadian clock 3, anticorps period circadian regulator 3, anticorps Per3, anticorps PER3

Sujet: Biological timepieces called circadian clocks are responsible for the regulation of hormonal rhythms, sleep cycles and other behaviors. The superchiasmatic nucleus (SCN), which is located in the brain, was the first mammalian circadian clock to be discovered. A number of transcription factors appearing to be molecular components of the SCN clock have been identified. Mutations within the Clock gene increase the length of the endogenous period and cause a loss of rhythmicity of circadian oscillations. Three mammalian period proteins, designated Per1, Per2 and Per3, exhibit circadian rhythyms in the SCN.During subjective night, Per1 and Per2 RNA levels increase in response to light pulses while Per3 RNA levels show no change in response to light pulses. Tim, for timeless, interacts with Per1 as well as Per2, and Tim and Per1 negatively regulate Clock-BMAL1-induced transcription.Synonyms: Cell growth-inhibiting gene 13 protein, Circadian clock protein PERIOD 3, GIG13, Period circadian protein homolog 3, hPER3

Poids moléculaire: approx. 43 kDa

ID gène: 8863

NCBI Accession: NP_058515

UniProt: P56645