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FOXE3 anticorps

FOXE3 Reactivité: Humain, Souris, Rat WB, IHC (p) Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN498337
  • Antigène Voir toutes FOXE3 Anticorps
    FOXE3 (Forkhead Box E3 (FOXE3))
    Reactivité
    • 35
    • 13
    • 13
    • 1
    Humain, Souris, Rat
    Hôte
    • 35
    Lapin
    Clonalité
    • 35
    Polyclonal
    Conjugué
    • 14
    • 4
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp FOXE3 est non-conjugé
    Application
    • 24
    • 22
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Specificité
    This antibody detects endogenous levels of FOXE3 protein. (region surrounding Arg97)
    Réactivité croisée (Details)
    Species reactivity (expected):Mouse and Rat.
    Species reactivity (tested):Human.
    Purification
    Affinity chromatography
    Pureté
    > 95 % by SDS-PAGE
    Top Product
    Discover our top product FOXE3 Anticorps primaire
  • Indications d'application
    Western Blot: 1/500 - 1/1000. Immunohistochemistry: 1/50 - 1/200.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Restrictions
    For Research Use only
  • Concentration
    1.0 mg/mL
    Buffer
    Phosphate buffered saline (PBS) with 0.05 % Sodium azide, approx. pH 7.2.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Conseil sur la manipulation
    Avoid repeated freezing and thawing.
    Stock
    4 °C/-20 °C
    Stockage commentaire
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • Antigène
    FOXE3 (Forkhead Box E3 (FOXE3))
    Autre désignation
    FOXE3 / FKHL12 (FOXE3 Produits)
    Synonymes
    anticorps FOXE3, anticorps FKHL12, anticorps FREAC8, anticorps dyl, anticorps rct, anticorps FREAC-8, anticorps HFH7, anticorps HNF3, anticorps foxe4, anticorps lens1, anticorps lens1-A, anticorps forkhead box E3, anticorps forkhead box E3 L homeolog, anticorps foxe3, anticorps FOXE3, anticorps LOC100301611, anticorps Foxe3, anticorps foxe3.L
    Sujet
    The human forkhead-box (FOX) gene family consists of at least 43 members, including FOXE3, a 288-amino acid protein. FOXE3 is a winged-helix transcription factor that plays a crucial role during the initial stages of lens development and closure of the lens vesicle. FOXE3 may also act as a factor that promotes survival and proliferation while preventing differentiation in the lens epithelium. As the posterior cells of the lens fiber begin to differentiate, expression of FOXE3 is limited to the undifferentiated cells coating the anterior surface of the lens. Congenital primary aphakia (CPA) is a rare developmental disorder caused by a null mutation in the FOXE3 gene that is identified by the absence of a lens. The development of CPA is normally stimulated during the fourth or fifth week of human embryogenesis.Synonyms: FREAC8, Forkhead box protein E3, Forkhead-related protein FKHL12, Forkhead-related transcription factor 8
    Poids moléculaire
    approx. 33 kDa
    ID gène
    2301
    NCBI Accession
    NP_036318
    UniProt
    Q13461
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