XPNPEP1 anticorps (C-Term)

N° du produit ABIN499169

Détail du produit anti-XPNPEP1 anticorps

Antigène: XPNPEP1 (X-Prolyl Aminopeptidase (Aminopeptidase P) 1, Soluble (XPNPEP1))

Épitope: C-Term

Reactivité: Humain, Souris, Rat, Porc, Chien, Boeuf (Vache)

Hôte: Chèvre

Clonalité: Polyclonal

Conjugué: Cet anticorp XPNPEP1 est non-conjugé

Application: Western Blotting (WB)

Séquence: C-LIRETQPISK QH

Specificité: This antibody detects XPNPEP1 at C-term. It is expected to recognize isoform 1 and 2 (NP_065116.2, NP_001161076.1).

Réactivité croisée (Details): Species reactivity (expected):Mouse, rat, cow, pigSpecies reactivity (tested):Human

Purification: Ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide

Immunogène: Peptide from the C Terminus of the protein sequence according to NP_065116.2, NP_001161076.1

Information d'application

Indications d'application: Peptide ELISA: limit dilution 1: 32000. Western blot: 0.3-1 μg/mL. Approx 80 kDa band observed in Human Heart, Skeletal Muscleand Pancreas lysates (calculated MW of 69.0 kDa according to NP_065116.2).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 0.5 mg/mL

Buffer: Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store at 2 - 8 °C up to one week or (in aliquots) at -20 °C for longer.

Détails sur XPNPEP1

Antigène: XPNPEP1 (X-Prolyl Aminopeptidase (Aminopeptidase P) 1, Soluble (XPNPEP1))

Autre désignation: XPNPEP1 (XPNPEP1 Produits)

Synonymes: anticorps APP1, anticorps SAMP, anticorps XPNPEP, anticorps XPNPEPL, anticorps XPNPEPL1, anticorps D230045I08Rik, anticorps sAMP, anticorps X-prolyl aminopeptidase 1, anticorps X-prolyl aminopeptidase (aminopeptidase P) 1, soluble, anticorps XPNPEP1, anticorps Xpnpep1

Sujet: XPNPEP1 is a proline-specific metalloaminopeptidase that specifically catalyzes the removal of any unsubstituted N-terminal amino acid that is adjacent to a penultimate proline residue. As a result of its specificity toward proline, it has been suggested that XPNPEP1 is important in the maturation and degradation of peptide hormones, neuropeptides, and tachykinins, as well as in the digestion of otherwise resistant dietary protein fragments, thereby complementing the pancreatic peptidases. Deficiency of XPNPEP1 results in excretion of large amounts of imino-oligopeptides in urine.Synonyms: Aminoacylproline aminopeptidase, Cytosolic aminopeptidase P, Soluble aminopeptidase P, X-Pro aminopeptidase 1, X-prolyl aminopeptidase 1 soluble, XPNPEPL, XPNPEPL1, Xaa-Pro aminopeptidase 1

ID gène: 7511

NCBI Accession: NP_065116

UniProt: Q9NQW7