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ADAM10 anticorps (C-Term)

ADAM10 Reactivité: Humain WB, IF, EIA Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN499211
  • Antigène Voir toutes ADAM10 Anticorps
    ADAM10 (ADAM Metallopeptidase Domain 10 (ADAM10))
    Épitope
    • 15
    • 5
    • 5
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reactivité
    • 68
    • 33
    • 33
    • 1
    • 1
    • 1
    Humain
    Hôte
    • 53
    • 15
    • 2
    • 1
    Lapin
    Clonalité
    • 46
    • 25
    Polyclonal
    Conjugué
    • 37
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp ADAM10 est non-conjugé
    Application
    • 49
    • 18
    • 16
    • 15
    • 13
    • 13
    • 8
    • 7
    • 7
    • 7
    • 5
    • 3
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (IF), Enzyme Immunoassay (EIA)
    Specificité
    ADAM10 antibody was raised against a peptide corresponding to amino acids 732 to 748 of human ADAM10. This sequence is identical to those of bovine and rat origins and differs from that of mouse ADAM10 by one amino acid (2,4).
    Purification
    Ion exchange chromatography
    Immunogène
    Human ADAM10 (C-Terminus) Peptide
    Isotype
    IgG
    Top Product
    Discover our top product ADAM10 Anticorps primaire
  • Indications d'application
    ELISA. Western Blot: ADAM10 can be used for detection of ADAM10 at 1: 500 to 1: 2000 dilution. Anapproximately 85 kDa band can be detected, which may represent precursor. Immunocytochemistry: 2,0 μg/mL
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Restrictions
    For Research Use only
  • Buffer
    PBS containing 0.02 % Sodium Azide as preservative
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Conseil sur la manipulation
    Avoid repeated freezing and thawing.
    Stock
    4 °C/-20 °C
    Stockage commentaire
    Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • Antigène
    ADAM10 (ADAM Metallopeptidase Domain 10 (ADAM10))
    Autre désignation
    CD156c / ADAM10 (ADAM10 Produits)
    Synonymes
    anticorps ADAM10, anticorps Adam10, anticorps adam10, anticorps wu:fc03d12, anticorps ad10, anticorps cd156c, anticorps kuz, anticorps kuzbanian, anticorps madm, anticorps xadam10, anticorps ADAM-10, anticorps ADAM 10, anticorps AD10, anticorps CD156c, anticorps HsT18717, anticorps MADM, anticorps 1700031C13Rik, anticorps LOC100219653, anticorps zgc:64203, anticorps ADAM metallopeptidase domain 10, anticorps ADAM metallopeptidase domain 10a, anticorps ADAM metallopeptidase domain 10 S homeolog, anticorps a disintegrin and metallopeptidase domain 10, anticorps ADAM metallopeptidase domain 10b, anticorps ADAM10, anticorps Adam10, anticorps adam10a, anticorps adam10.S, anticorps adam10b
    Sujet
    Proinflammatory cytokine tumor necrosis factor-alpha (TNF-alpha) contributes to a variety of inflammatory responses and programmed cell death. Notch receptor and its ligand participate in cell fate decisions during vertebrate development and are associated with several human disorders, including a T-cell lymphoma. TNF-alpha, notch and its ligand delta are all membrane-bond molecules, which are cleaved by proteases to release mature proteins or functional receptor. ADAM10, a metalloprotease-disintegrin in the family of mammalian ADAM (for a disintegrin and metalloprotease), was recently identified to cleave TNF-alpha, notch and its ligand delta (1-3). The genes encoding human, mouse, and bovine ADAM10 were recently cloned and designated ADAM 10, kuzbanian (KUZ), and MADM, respectively, (1,2,4). ADAM10 mRNA is expressed in a variety of human and bovine tissues (1,4).Synonyms: Disintegrin and metalloproteinase domain-containing protein 10, KUZ, Kuzbanian protein homolog, MADM, Mammalian disintegrin-metalloprotease
    ID gène
    102
    NCBI Accession
    NP_001101
    UniProt
    O14672
    Pathways
    Signalisation Notch, EGFR Signaling Pathway
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