BAFF anticorps (C-Term)

N° du produit ABIN499401

Détail du produit anti-BAFF anticorps

Antigène: BAFF (TNFSF13B) (Tumor Necrosis Factor (Ligand) Superfamily, Member 13b (TNFSF13B))

Épitope: C-Term

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp BAFF est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF), Enzyme Immunoassay (EIA)

Specificité: Recognizes BAFF

Purification: Ion Exchange Chromatography

Immunogène: A peptide corresponding to amino acids near the carboxy terminus of Human BAFF

Isotype: IgG

Information d'application

Indications d'application: ELISA. Western Blot: BAFF antibody can be used for detection of BAFF at 0.25 to 1 μg/mL. Immunocytochemistry.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: PBS, 0.02 % Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur BAFF

Antigène: BAFF (TNFSF13B) (Tumor Necrosis Factor (Ligand) Superfamily, Member 13b (TNFSF13B))

Autre désignation: CD257 / BAFF (TNFSF13B Produits)

Synonymes: anticorps BAFF, anticorps BLYS, anticorps CD257, anticorps DTL, anticorps TALL-1, anticorps TALL1, anticorps THANK, anticorps TNFSF20, anticorps ZTNF4, anticorps BAFF-R, anticorps BAFFR, anticorps BROMIX, anticorps CD268, anticorps CVID4, anticorps prolixin, anticorps TNFSF13B, anticorps RGD1561519, anticorps RGD1560810, anticorps BLyS, anticorps D8Ertd387e, anticorps zTNF4, anticorps 2010006P15Rik, anticorps Baffr, anticorps Bcmd, anticorps Bcmd-1, anticorps Bcmd1, anticorps Lvis22, anticorps zgc:172115, anticorps TNF superfamily member 13b, anticorps TNF receptor superfamily member 13C, anticorps tumor necrosis factor (ligand) superfamily, member 13b, anticorps tumor necrosis factor receptor superfamily, member 13c, anticorps tumor necrosis factor superfamily member 13b, anticorps TNFSF13B, anticorps TNFRSF13C, anticorps Tnfsf13b, anticorps Tnfrsf13c, anticorps tnfsf13b

Sujet: Members in the TNF superfamily regulate immune responses and induce apoptosis. A novel member in the TNF family was recently identified by several groups and designated BAFF (for B cell Activating Factor belonging to the TNF Family), BLyS (for B Lymphocyte Stimulator), TALL-1 (for TNF- and ApoL-related Leukocyte-expressed Ligand), and THANK (for TNF Homologue that Activate Apoptosis, NF-kappaB and c-jun N-terminal Kinase) (1-4). BAFF/BLyS was characterized as a B cell activator since it induced B cell proliferation and immunoglobulin secretion (1,2). Three receptors for BAFF were recently identified and designated TACI, BCMA and BAFF-R (5,6). BAFF and its receptors are essential for B cell development, survival, and humoral immune responses. BAFF is involved in the development of autoimmune diseases including systemic lupus erythaematosus and rheumatoid arthritis (5).Synonyms: B cell-activating factor, B lymphocyte stimulator, BAFF, BLYS, Dendritic cell-derived TNF-like molecule, TALL1, TNF- and APOL-related leukocyte expressed ligand 1, TNFSF13B, TNFSF20, Tumor necrosis factor ligand superfamily member 13B, ZTNF4

ID gène: 10673

NCBI Accession: NP_006564

UniProt: Q9Y275

Pathways: Signalisation NF-kappaB, Production of Molecular Mediator of Immune Response