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Caspase 10 anticorps (C-Term)

CASP10 Reactivité: Humain WB, EIA Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN499545
  • Antigène Voir toutes Caspase 10 (CASP10) Anticorps
    Caspase 10 (CASP10) (Caspase 10, Apoptosis-Related Cysteine Peptidase (CASP10))
    Épitope
    • 16
    • 4
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reactivité
    • 70
    • 16
    • 6
    Humain
    Hôte
    • 61
    • 5
    • 2
    • 1
    • 1
    Lapin
    Clonalité
    • 55
    • 15
    Polyclonal
    Conjugué
    • 38
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp Caspase 10 est non-conjugé
    Application
    • 36
    • 19
    • 18
    • 13
    • 13
    • 12
    • 11
    • 10
    • 9
    • 4
    • 3
    • 2
    • 1
    Western Blotting (WB), Enzyme Immunoassay (EIA)
    Specificité
    Caspase-10 antibody was raised against a peptide corresponding to amino acids 505 to 521 of human FLICE2. Antibody only recognizes FLICE2 form of caspase-10.
    Purification
    DEAE
    Immunogène
    Human Caspase-10 (C-Terminus) Peptide
    Isotype
    IgG
    Top Product
    Discover our top product CASP10 Anticorps primaire
  • Indications d'application
    ELISA. Western Blot: Caspase-10 antibody can be used for detection of caspase-10 at 1/500 to1/1000 dilution. A 59 kDa band can be detected.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Restrictions
    For Research Use only
  • Buffer
    PBS containing 0.02 % sodium azide.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C
    Stockage commentaire
    Store the antibody undiluted at 2-8 °C.
  • Antigène
    Caspase 10 (CASP10) (Caspase 10, Apoptosis-Related Cysteine Peptidase (CASP10))
    Autre désignation
    Caspase-10 (CASP10 Produits)
    Synonymes
    anticorps xCaspase-10, anticorps alps2, anticorps caspace-10, anticorps caspase-10, anticorps flice2, anticorps mch4, anticorps xCaspace-10, anticorps ALPS2, anticorps FLICE2, anticorps MCH4, anticorps caspase 10 S homeolog, anticorps caspase 10, anticorps caspase-10, anticorps casp10.S, anticorps casp10, anticorps CASP10, anticorps Casp10, anticorps LOC100848685
    Sujet
    Apoptosis is related to many diseases and induced by a family of cell death receptors and their ligands. Cell death signals are transduced by death domain (DD)- containing adapter molecules and members of the ICE/CED-3 protease family. A novel ICE/CED-3 protease was identified recently, designated FLICE2 and Mch41,2 and renamed as caspase-10. Caspase-10 has two death effector domains (DEDs) that bind to the DED in the adapter molecule FADD and recruits both TNFR1 and CD95 to form complexes with these receptors. Caspase-10 is therefore involved in the CD95 and TNFR1 induced apoptosis1. Caspase-10 cleaves and activates caspase-3, -4, -6, -7, -8 and -9, which causes the proteolytic cleavage of many key proteins such as PARP. Cleavage of PARP occurs in many different systems during apoptosis and is the hallmark of programmed cell death. Caspase-10 is expressed in many tissues and cell lines.Synonyms: Apoptotic protease Mch-4, CASP-10, CASP10, FAS-associated death domain protein interleukin-1B-converting enzyme 2, FLICE2, ICE-like apoptotic protease 4, MCH4
    ID gène
    843
    UniProt
    Q92851
    Pathways
    Apoptose, Caspase Cascade in Apoptosis
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