Cathelicidin anticorps (C-Term)

N° du produit ABIN499581

Détail du produit anti-Cathelicidin anticorps

Antigène: Cathelicidin (CAMP) (Cathelicidin Antimicrobial Peptide (CAMP))

Épitope: C-Term

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Cathelicidin est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Specificité: This antibody detects Cathelicidin.

Purification: Peptide Affinity Chromatography

Immunogène: Cathelicidin antibody was raised against a 17 amino acid peptide near the carboxy terminus of the Human Cathelicidin.

Isotype: IgG

Information d'application

Indications d'application: ELISA. Western Blot: Cathelicidin antibody can be used for detection of Cathelicidin at 1 μg/mL. Immunohistochemistry.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: PBS containing 0.02 % Sodium Azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C.

Détails sur Cathelicidin

Antigène: Cathelicidin (CAMP) (Cathelicidin Antimicrobial Peptide (CAMP))

Autre désignation: CAMP / CAP18 (CAMP Produits)

Synonymes: anticorps CAP-18, anticorps CAP18, anticorps CRAMP, anticorps FALL-39, anticorps FALL39, anticorps LL37, anticorps CATH-2, anticorps Cnlp, anticorps Cramp, anticorps MCLP, anticorps CATH-B1, anticorps CATHB1, anticorps CATHL2, anticorps CATHL7, anticorps CAP11, anticorps cathelicidin antimicrobial peptide, anticorps CAMP, anticorps LOC100136187, anticorps LOC100136439, anticorps Camp

Sujet: One component of host defense at mucosal surfaces is epithelial-derived antimicrobial peptides. Cathelicidins are one family of antimicrobial peptides characterized by conserved pro-peptide sequences that have been identified in epithelial tissues and some myeloid cells of humans and animals. LL-37/hCAP-18 is the only Cathelicidin found in humans and is expressed in inflammatory and epithelial cells. The presence of these molecules is essential for defense against invasive bacterial infection in skin. Besides their direct antimicrobial function, Cathelicidins have multiple roles in mediating innate and adaptive immunity, such as endotoxin neutralizing, angiogenesis, wound healing and promoting neutrophil chemotaxis and mast cell recruitment. Finally, Cathelicidin antimicrobial peptides qualify as prototypes of innovative drugs that may be used to treat infection and/or modulate the immune response.Synonyms: 18 kDa cationic antimicrobial protein, Antibacterial protein LL-37, CAP-18, Cathelicidin antimicrobial peptide, FALL-39, FALL39, HSD26, hCAP-18

ID gène: 820

NCBI Accession: NP_004336

UniProt: P49913

Pathways: Cellular Response to Molecule of Bacterial Origin