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TMC6 anticorps (N-Term)

TMC6 Reactivité: Humain, Souris, Rat WB, IHC (p), EIA Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN499806
  • Antigène Voir toutes TMC6 Anticorps
    TMC6 (Transmembrane Channel-Like 6 (TMC6))
    Épitope
    • 8
    • 7
    • 5
    • 1
    • 1
    • 1
    • 1
    N-Term
    Reactivité
    Humain, Souris, Rat
    Hôte
    • 16
    Lapin
    Clonalité
    • 16
    Polyclonal
    Conjugué
    • 6
    • 2
    • 2
    • 2
    • 2
    • 2
    Cet anticorp TMC6 est non-conjugé
    Application
    • 16
    • 13
    • 2
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
    Specificité
    This antibody reacts to EVER1.
    Purification
    Affinity chromatography purified via peptide column
    Immunogène
    EVER1 antibody was raised against a 14 amino acid peptide from near the amino terminus of human EVER1.
    Isotype
    IgG
  • Indications d'application
    ELISA. Western Blot: 1 - 2 μg/mL. Immunohistochemistry.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Restrictions
    For Research Use only
  • Buffer
    PBS containing 0.02 % sodium azide.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C
    Stockage commentaire
    Store the antibody undiluted at 2-8 °C.
  • Antigène
    TMC6 (Transmembrane Channel-Like 6 (TMC6))
    Autre désignation
    TMC6 / EVER1 (TMC6 Produits)
    Synonymes
    anticorps EVER1, anticorps zgc:92610, anticorps MGC83549, anticorps ever1, anticorps EV1, anticorps EVIN1, anticorps LAK-4P, anticorps D11Ertd204e, anticorps transmembrane channel like 6, anticorps transmembrane channel-like 6b, anticorps transmembrane channel like 6 L homeolog, anticorps transmembrane channel-like gene family 6, anticorps TMC6, anticorps tmc6b, anticorps tmc6.L, anticorps tmc6, anticorps Tmc6
    Sujet
    Epidermodysplasia verruciformis (EV) is an autosomal recessive dermatosis characterized by abnormal susceptibility to human papillomaviruses (HPVs) and a high rate of progression to squamous cell carcinoma on sun-exposed skin. EV is caused by mutations in either of two adjacent genes, EVER1 and EVER2, located on chromosome 17q25.3. Both of these genes encode integral membrane proteins that localize to the endoplasmic reticulum and are predicted to form transmembrane channels. Both EVER1 and EVER2 are members of the transmembrane channel-like (TMC) protein family. EVER1 possesses eight trans-membrane domains and two leucine zipper motifs. EVER1 and EVER2 form a complex and interact with the zinc transporter 1 (ZnT-1), suggesting that EVER1 and EVER2 act to regulate cellular zinc balance. At least four isoforms of EVER1 are known to exist. This EVER1 antibody does not cross-react with EVER2.Synonyms: EVIN1, Epidermodysplasia verruciformis protein 1, LAK-4, Transmembrane channel-like protein 6
    ID gène
    11322
    UniProt
    Q7Z403
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