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FLIP anticorps (C-Term)

CFLAR Reactivité: Humain WB, IF, EIA Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN499850
  • Antigène Voir toutes FLIP (CFLAR) Anticorps
    FLIP (CFLAR) (CASP8 and FADD-Like Apoptosis Regulator (CFLAR))
    Épitope
    • 16
    • 15
    • 15
    • 10
    • 7
    • 5
    • 5
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reactivité
    • 96
    • 67
    • 57
    • 2
    • 1
    • 1
    • 1
    Humain
    Hôte
    • 86
    • 15
    • 2
    Lapin
    Clonalité
    • 88
    • 15
    Polyclonal
    Conjugué
    • 55
    • 5
    • 5
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 1
    Cet anticorp FLIP est non-conjugé
    Application
    • 98
    • 39
    • 27
    • 26
    • 21
    • 20
    • 14
    • 14
    • 13
    • 10
    • 8
    • 5
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (IF), Enzyme Immunoassay (EIA)
    Specificité
    FLIP antibody was raised against a peptide corresponding to amino acids 191 to 209 at C-terminus of human FLIP form2. Antibody recognizes FLIPgamma and FLIPdelta but not FLIPalpha and FLIPbeta.
    Purification
    Affinity chromatography purified via peptide column
    Immunogène
    Human FLIP (C-Terminus) Peptide
    Isotype
    IgG
    Top Product
    Discover our top product CFLAR Anticorps primaire
  • Indications d'application
    ELISA. Western Blot: 1/1000.35 kDa and 25 kDa bands can be detected. Immunocytochemistry.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Restrictions
    For Research Use only
  • Buffer
    PBS containing 0.02 % sodium azide.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C
    Stockage commentaire
    Store the antibody undiluted at 2-8 °C.
  • Antigène
    FLIP (CFLAR) (CASP8 and FADD-Like Apoptosis Regulator (CFLAR))
    Autre désignation
    CFLAR / Casper / I-FLICE (CFLAR Produits)
    Synonymes
    anticorps Clarp1, anticorps cflar, anticorps CFLAR, anticorps FLIP, anticorps CASH, anticorps CASP8AP1, anticorps CLARP, anticorps Casper, anticorps FLAME, anticorps FLAME-1, anticorps FLAME1, anticorps I-FLICE, anticorps MRIT, anticorps c-FLIP, anticorps c-FLIPL, anticorps c-FLIPR, anticorps c-FLIPS, anticorps 2310024N18Rik, anticorps A430105C05Rik, anticorps Cash, anticorps ENSMUSG00000072980, anticorps Flip, anticorps Gm9845, anticorps c-Flip, anticorps CASP8 and FADD-like apoptosis regulator a, anticorps CASP8 and FADD like apoptosis regulator, anticorps CASP8 and FADD like apoptosis regulator S homeolog, anticorps CASP8 and FADD-like apoptosis regulator, anticorps cflara, anticorps CFLAR, anticorps cflar, anticorps cflar.S, anticorps Cflar
    Sujet
    Apoptosis is related to many diseases and induced by a family of cell death receptors and their ligands. Cell death signals are transduced by death domain (DD)-containing adapter molecules and members of the ICE/CED-3 protease family. Caspases-8 (FLICE) and -10 (FLICE2) are two pivotal members in the ICE/CED-3 protease family. FLICE-inhibitory proteins were identified in virus and human and designated v-FLIPs and c-FLIPs, respectively1,2. The human FLIPs were also cloned by several labs independently and termed Casper , I-FLICE, FLAME-1, CASH, CLARP and usurpin3-7. FLIP contains two death effector domains (DEDs) and a caspase-like domain. FLIP interacts with adapter protein FADD and caspase-8 and 10, and potently inhibits apoptosis induced by all known death receptors CD95, DR3, TRAIL-R and TNFR1. Four splice variants of c-FLIPs have been identified and termed FLIPalpha, beta, gamma, and delta, respectively (8).Synonyms: CASH, CASP8 and FADD-like apoptosis regulator, CASP8AP1, CLARP, Caspase homolog, Caspase-eight-related protein, Caspase-like apoptosis regulatory protein, Cellular FLICE-like inhibitory protein, FADD-like antiapoptotic molecule 1, FLAME-1, Inhibitor of FLICE, MACH-related inducer of toxicity, MRIT, Usurpin, c-FLIP
    ID gène
    8837
    UniProt
    O15519
    Pathways
    Apoptose, Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development
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