GFRA1 anticorps (Intermediate Domain)

N° du produit ABIN499883

Détail du produit anti-GFRA1 anticorps

Antigène: GFRA1 (GDNF Family Receptor alpha 1 (GFRA1))

Épitope: Intermediate Domain

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp GFRA1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Specificité: GFR alpha 1 antibody was raised against a peptide corresponding to amino acids 369 to 382 of human GFR alpha 1.

Purification: DEAE Chromatography

Immunogène: Human GFR alpha 1 (Intermediate Domain) Peptide

Isotype: IgG

Information d'application

Indications d'application: ELISA. Western Blot. Immunohistochemistry.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C.

Détails sur GFRA1

Antigène: GFRA1 (GDNF Family Receptor alpha 1 (GFRA1))

Autre désignation: GFRA1 / GDNFR-alpha (GFRA1 Produits)

Synonymes: anticorps gdnfr, anticorps ret1l, anticorps retl1, anticorps trnr1, anticorps gdnfra, anticorps MGC122616, anticorps gfr-alpha-1, anticorps GDNFR, anticorps GDNFRA, anticorps GFR-ALPHA-1, anticorps RET1L, anticorps RETL1, anticorps TRNR1, anticorps GDNFRALPHA, anticorps GFRA1, anticorps AU042498, anticorps gfralpha1a, anticorps zgc:110129, anticorps GDNF family receptor alpha 1, anticorps glial cell line derived neurotrophic factor family receptor alpha 1, anticorps gdnf family receptor alpha 1a, anticorps gfra1, anticorps GFRA1, anticorps Gfra1, anticorps gfra1a

Sujet: Glial cell line-derived neurotrophic factor (GDNF) is a potent survival factor for central and peripheral neurons and is essential for the development of kidneys and the enteric nerves system. Physiological responses to GDNF require the presence of a novel glycosylphosphadidylinositol linked protein GDNFRa, which is a cell surface receptor for GDNF. The cDNAs encoding GDNFRalpha from human, rat, chicken and mouse have been cloned recently. GDNFRalpha was also termed Ret ligand 1 (RETL1) or TGF-beta-related neurotrophic factor receptor 1 (TrnR1) and nominated as GFRalpha-1 recently. GFRalpha-1 binds GDNF specifically and mediates activation of the Ret protein tyrosine kinase (PTK). Thus, GDNF, GFRalpha and the Ret PTK form a complex to transduce GDNF signal and to mediate GDNF function.Synonyms: GDNF family receptor alpha-1, GDNF receptor alpha, GDNFRA, GFR-alpha-1, RET ligand 1, RETL1, TGF-beta-related neurotrophic factor receptor 1, TRNR1

ID gène: 2674

UniProt: P56159