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IL27 anticorps (Center)

IL27 Reactivité: Humain, Souris WB, EIA Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN500002
  • Antigène Voir toutes IL27 Anticorps
    IL27 (Interleukin-27 Subunit alpha (IL27))
    Épitope
    • 2
    • 2
    • 1
    • 1
    • 1
    Center
    Reactivité
    • 17
    • 14
    • 10
    Humain, Souris
    Hôte
    • 16
    • 4
    Lapin
    Clonalité
    • 16
    • 4
    Polyclonal
    Conjugué
    • 11
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp IL27 est non-conjugé
    Application
    • 8
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    Western Blotting (WB), Enzyme Immunoassay (EIA)
    Specificité
    This antibody reacts to IL-27.
    Purification
    Affinity chromatography purified via peptide column
    Immunogène
    IL-27 antibody was raised against a 14 amino acid peptide from near the center of human IL-27.
    Isotype
    IgG
    Top Product
    Discover our top product IL27 Anticorps primaire
  • Indications d'application
    ELISA. Western Blot: 2 - 4 μg/mL.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Restrictions
    For Research Use only
  • Buffer
    PBS containing 0.02 % sodium azide.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C
  • Antigène
    IL27 (Interleukin-27 Subunit alpha (IL27))
    Autre désignation
    Interleukin-27 / IL27A (IL27 Produits)
    Synonymes
    anticorps IL-27, anticorps IL-27A, anticorps IL27A, anticorps IL27p28, anticorps IL30, anticorps p28, anticorps EUROIMAGE1875335, anticorps IL25, anticorps IL27, anticorps IL27w, anticorps R33729_1, anticorps SF20, anticorps IL-27p28, anticorps Il30, anticorps interleukin 27, anticorps myeloid derived growth factor, anticorps IL27, anticorps MYDGF, anticorps Il27
    Sujet
    Like interleukin-23 (IL-23), IL-27 is a recently discovered member of the IL-6/IL-12 family of proinflammatory and immunoregulatory cytokines. It exists as a heterodimer composed of the p40-related protein EBI3 and an IL-12 p35-related protein termed p28. IL-27 is produced after activation by antigen-presenting cells and induces proliferation of naive but not memory CD4+ T-cells. It acts by binding to its receptor WSX-1 and gp130 which results in the activation of a Jak/STAT signaling cascade, suggesting the IL-27 is involved in the regulation of immune processes. It has been suggested that IL-27 can also be used as a therapeutic agent against cancer as it can also induce tumor-specific anti-tumor activity mediated through CD8+ T-cells, IFN-γ, and T-bet.Synonyms: IL-27 subunit alpha, IL-30, IL27-A, IL30, Interleukin-30, p28
    ID gène
    246778
    NCBI Accession
    NP_663634
    UniProt
    Q8NEV9
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