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Neurturin anticorps (AA 178-193)

NRTN Reactivité: Humain WB, EIA, IHC (p) Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN500336
  • Antigène Voir toutes Neurturin (NRTN) Anticorps
    Neurturin (NRTN)
    Épitope
    • 15
    • 7
    • 6
    • 6
    • 6
    • 6
    • 2
    • 2
    • 1
    AA 178-193
    Reactivité
    • 47
    • 21
    • 16
    • 15
    • 5
    • 2
    • 2
    • 1
    • 1
    • 1
    Humain
    Hôte
    • 42
    • 3
    • 2
    • 2
    Lapin
    Clonalité
    • 46
    • 3
    Polyclonal
    Conjugué
    • 23
    • 5
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp Neurturin est non-conjugé
    Application
    • 47
    • 26
    • 13
    • 13
    • 6
    • 4
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB), Enzyme Immunoassay (EIA), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Specificité
    This antibody detects Neurturin.
    Réactivité croisée (Details)
    Species reactivity (tested):Human
    Purification
    Peptide affinity chromatography
    Immunogène
    Neurturin antibody was raised against a peptide corresponding to amino acids 178 to 193 of human neurturin.
    Isotype
    IgG
    Top Product
    Discover our top product NRTN Anticorps primaire
  • Indications d'application
    ELISA. Western blot. Immunohistochemistry on paraffin sections.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Restrictions
    For Research Use only
  • Buffer
    PBS containing 0.02 % sodium azide
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Conseil sur la manipulation
    Avoid repeated freezing and thawing.
    Stock
    4 °C/-20 °C
    Stockage commentaire
    Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
  • Antigène
    Neurturin (NRTN)
    Autre désignation
    Neurturin (NRTN Produits)
    Synonymes
    anticorps NRTN, anticorps NTN, anticorps neurturin, anticorps NRTN, anticorps Nrtn
    Sujet
    Glial cell line-derived neurotrophic factor (GDNF) plays key roles in the control of vertebrate neuron survival and differentiation. A novel neurotrophic factor was recently cloned from human and mouse and designated neurturin. Physiological responses to neurturin (NTN) require the presence of receptor tyrosine kinase RET and a novel glycosylphosphatidylinositol linked receptor NTNRalpha. The cDNAs encoding NTNRalpha from human, rat, chicken, and mouse have been cloned recently (3-8) and termed GDNFRb, Ret ligand 2 (RETL2) or TGF-Β-related neurotrophic factor receptor 2 (TrnR2) and nominated as GFRalpha-2 recently. NTN binds to and forms a complex with GFRalpha-2 and the Ret PTK and activates the RET receptor tyrosine kinase pathway. Both NTN and GDNF can activate the MAP kinase and phosphatidylinositol 3-kinase pathways and play a critical role in the development of many neuronal populations. Neurturin and GDNF define a new family of neurotrophic factors.Synonyms: NRTN
    ID gène
    4902
    NCBI Accession
    NP_004549
    UniProt
    Q99748
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