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RAPTOR anticorps (C-Term)

RAPTOR Reactivité: Souris WB, IF, EIA Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN500571
  • Antigène Voir toutes RAPTOR Anticorps
    RAPTOR
    Épitope
    • 16
    • 15
    • 15
    • 6
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reactivité
    • 64
    • 44
    • 25
    • 15
    • 1
    Souris
    Hôte
    • 63
    • 3
    Lapin
    Clonalité
    • 62
    • 4
    Polyclonal
    Conjugué
    • 21
    • 5
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    Cet anticorp RAPTOR est non-conjugé
    Application
    • 30
    • 26
    • 26
    • 26
    • 9
    • 8
    • 7
    • 6
    • 6
    • 3
    • 3
    • 3
    • 2
    Western Blotting (WB), Immunofluorescence (IF), Enzyme Immunoassay (EIA)
    Réactivité croisée (Details)
    Species reactivity (tested):Mouse
    Purification
    Peptide affinity chromatography
    Immunogène
    Raptor (CT) polyclonal antibody was raised against a 16 amino acid peptide from near the carboxy-terminus of mouse Raptor.
    Isotype
    IgG
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    Discover our top product RAPTOR Anticorps primaire
  • Indications d'application
    ELISA. Western blot: 2 μg/mL. Immunocytochemistry.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Restrictions
    For Research Use only
  • Buffer
    PBS containing 0.02 % sodium azide
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Conseil sur la manipulation
    Avoid repeated freezing and thawing.
    Stock
    4 °C/-20 °C
    Stockage commentaire
    Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
  • Antigène
    RAPTOR
    Autre désignation
    RAPTOR (RAPTOR Produits)
    Synonymes
    anticorps KOG1, anticorps Mip1, anticorps 4932417H02Rik, anticorps Rap, anticorps Raptor, anticorps mKIAA1303, anticorps RGD1311784, anticorps regulatory associated protein of MTOR complex 1, anticorps regulatory associated protein of MTOR, complex 1, anticorps RPTOR, anticorps Rptor
    Sujet
    The mammalian Target of Rapamycin (TOR, also known as mTOR) is an evolutionarily conserved serine/threonine kinase that regulates cell growth and cell cycle through its ability to integrate signals from nutrient levels and growth factors (reviewed in 1). Rapamycin inhibits TOR activity resulting in reduced cell growth and reduced rates of cell cycle and cell proliferation (reviewed in 2). Raptor (regulatory associated protein of TOR) is a TOR-binding protein essential for TOR signaling in vivo. It acts as a TOR scaffold protein whose binding by TOR substrates is necessary for effective TOR-catalyzed phosphorylation (3). These substrates include the ribosomal protein S6 kinase (RP S6K) and the eukaryotic initiation factor 4E binding protein 4EBP1, proteins necessary for cell growth and proliferation and responsive to nutrient and mitogen levels (4). Raptor binds these proteins through a common 5 amino acid TOR-signaling (TOS) motif, mutation of this motif prevents the TOR-dependent phosphorylation of these proteins (5).Synonyms: KIAA1303, P150 target of rapamycin TOR-scaffold protein, RPTOR, Regulatory-associated protein of mTOR
    UniProt
    Q8K4Q0
    Pathways
    L'effet Warburg
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