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SIRT2 anticorps (C-Term)

SIRT2 Reactivité: Humain, Rat, Souris WB, IHC (p), EIA Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN500724
  • Antigène Voir toutes SIRT2 Anticorps
    SIRT2 (Sirtuin 2 (SIRT2))
    Épitope
    • 6
    • 5
    • 5
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reactivité
    • 60
    • 40
    • 36
    • 8
    • 4
    • 4
    • 4
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Humain, Rat, Souris
    Hôte
    • 58
    • 10
    • 1
    Lapin
    Clonalité
    • 48
    • 21
    Polyclonal
    Conjugué
    • 45
    • 7
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    Cet anticorp SIRT2 est non-conjugé
    Application
    • 49
    • 19
    • 12
    • 12
    • 12
    • 10
    • 6
    • 2
    • 2
    • 2
    • 2
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
    Specificité
    This antibody detects SIRT2 / SIR2 at C-term.
    Réactivité croisée (Details)
    Species reactivity (tested):Human, Mouse, Rat
    Purification
    Peptide Affinity Chromatography
    Immunogène
    SIRT2 antibody was raised against a 19 amino acid peptide near the carboxy terminus of the Human SIRT2.
    Isotype
    IgG
    Top Product
    Discover our top product SIRT2 Anticorps primaire
  • Indications d'application
    ELISA. Western blot: 1-2 μg/mL. Immunohistochemistry on Paraffin Sections. Positive Control: Mouse Brain Tissue Lysate.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Restrictions
    For Research Use only
  • Buffer
    PBS containing 0.02 % Sodium Azide
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C
    Stockage commentaire
    Store the antibody undiluted at 2-8 °C.
  • Antigène
    SIRT2 (Sirtuin 2 (SIRT2))
    Autre désignation
    SIRT2 / SIR2 (SIRT2 Produits)
    Synonymes
    anticorps CG5085, anticorps D.mel2, anticorps Dmel\\CG5085, anticorps SIRT2, anticorps dSIRT2, anticorps sir2, anticorps Sirt2, anticorps BmSirt2, anticorps AtSRT2, anticorps SIRTUIN 2, anticorps T2K12.8, anticorps sirtuin 2, anticorps SIR2, anticorps SIR2L, anticorps SIR2L2, anticorps 5730427M03Rik, anticorps Sir2l, anticorps wu:fb57d05, anticorps zgc:55966, anticorps zgc:77003, anticorps Sirtuin 2, anticorps sirtuin 2, anticorps sirtuin 2 S homeolog, anticorps NAD-dependent deacetylase sirtuin 2 homolog, anticorps sirtuin 2 (silent mating type information regulation 2, homolog) 2 (S. cerevisiae), anticorps Sirt2, anticorps SIRT2, anticorps sirt2.S, anticorps SRT2, anticorps sirt2
    Sujet
    The founding member of the sirtuin protein family was the silent information regulator 2 protein (Sir2p) of Saccharomyces cervisiae, an NAD+-dependent histone deacetylase (HDAC) that regulates chromatin silencing. The SIR2 family of genes are highly conserved from prokaryotes to eukaryotes. Mammals have seven homologs of Sir2p, SIRT1-7, which are involved in diverse processes ranging from transcriptional regulation, cell cycle progression and DNA-damage repair to aging. SIRT2 is a predominantly cytoplasmic protein that colocalizes with microtubules and can deacetylate ?-tubulin and regulate progression through the cell cycle. Most Sirtuins are highly expressed in brain and testis, while Sirt2 expression is higher in fetal relative to adult brain. Recent studies on SIRT2 support the therapeutic utility of inhibitors for the treatment of neurodegenerative diseases such as Parkinson's disease.Synonyms: NAD-dependent deacetylase sirtuin-2, SIR2-like protein 2, SIR2L, SIR2L2, SIRT-2, sirtuin (silent mating type information regulation 2 homolog) 2 (S. cerevisiae), sirtuin 2, sirtuin type 2, sirtuin-2
    ID gène
    22933
    NCBI Accession
    NP_036369
    UniProt
    Q8IXJ6
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