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GPR124 anticorps (C-Term)

GPR124 Reactivité: Humain, Rat WB, IHC (p), EIA Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN500895
  • Antigène Voir toutes GPR124 Anticorps
    GPR124 (G Protein-Coupled Receptor 124 (GPR124))
    Épitope
    • 15
    • 6
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reactivité
    • 26
    • 25
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    Humain, Rat
    Hôte
    • 41
    Lapin
    Clonalité
    • 41
    Polyclonal
    Conjugué
    • 17
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp GPR124 est non-conjugé
    Application
    • 17
    • 14
    • 14
    • 11
    • 10
    • 7
    • 5
    • 4
    • 2
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
    Specificité
    This antibody detects GPR124 / TEM5 at C-term.
    Réactivité croisée (Details)
    Species reactivity (tested):Human, rat
    Purification
    Peptide affinity chromatography
    Immunogène
    TEM5 antibody was raised against a 15 amino acid peptide near the carboxy terminus of the human TEM5.
    Isotype
    IgG
    Top Product
    Discover our top product GPR124 Anticorps primaire
  • Indications d'application
    ELISA. Western blot: 1 - 2 μg/mL. Immunohistochemistry on paraffin sections.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Restrictions
    For Research Use only
  • Buffer
    PBS containing 0.02 % sodium azide
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Conseil sur la manipulation
    Avoid repeated freezing and thawing.
    Stock
    4 °C/-20 °C
    Stockage commentaire
    Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
  • Antigène
    GPR124 (G Protein-Coupled Receptor 124 (GPR124))
    Autre désignation
    GPR124 / TEM5 (GPR124 Produits)
    Synonymes
    anticorps TEM5, anticorps 8430414O08Rik, anticorps 9530074E10Rik, anticorps Tem5, anticorps mKIAA1531, anticorps MGC69043, anticorps si:dkey-208c22.2, anticorps GPR124, anticorps adhesion G protein-coupled receptor A2, anticorps adhesion G protein-coupled receptor A2 L homeolog, anticorps G-protein coupled receptor 124, anticorps ADGRA2, anticorps Adgra2, anticorps adgra2.L, anticorps adgra2, anticorps LOC616111
    Sujet
    Tumor endothelial markers (TEMs) are significantly up-regulated during angiogenesis and neoangiogensis that are crucial for the growth of solid tumors. TEMs localized on the cell surface and conserved across species are of particular interest for future development of anti-angiogenic therapies. These include TEMs such as TEM1, TEM5, TEM7 and TEM8. TEM5 is a member of the adhesion family of G protein coupled receptors and is localized on the surface of endothelial cells. TEM5 is a seven-pass transmembrane receptor, unlike TEM1, TEM7 and TEM8 which span the membrane once. TEM5 is abundantly expressed in tumor vessels, heart, placenta, ovary, small intestine, and colon. Proteolytically processed soluble TEM5 mediates endothelial cell survival during angiogenesis by linking integrin to glycosaminoglycans.Synonyms: G-protein coupled receptor 124, KIAA1531, Tumor endothelial marker 5
    ID gène
    25960
    UniProt
    Q96PE1
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