TLR6 anticorps (N-Term)

N° du produit ABIN500958

Détail du produit anti-TLR6 anticorps

Antigène: TLR6 (Toll-Like Receptor 6 (TLR6))

Épitope: N-Term

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TLR6 est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF), Enzyme Immunoassay (EIA)

Specificité: This antibody detects CD286 / TLR6 at N-term.

Réactivité croisée (Details): Species reactivity (tested):Human, mouse

Purification: Peptide affinity chromatography

Immunogène: TLR6 antibody was raised against a peptide corresponding to 15 amino acids near the amino terminus of human TLR6.

Isotype: IgG

Information d'application

Indications d'application: ELISA. Western blot. Immunoflourescence.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Buffer: PBS containing 0.02 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.

Détails sur TLR6

Antigène: TLR6 (Toll-Like Receptor 6 (TLR6))

Autre désignation: CD286 / TLR6 (TLR6 Produits)

Synonymes: anticorps TLR1, anticorps TLR16, anticorps CD286, anticorps TLR-6, anticorps toll-like receptor 1 family member A, anticorps toll like receptor 6, anticorps toll-like receptor 6, anticorps TLR1A, anticorps TLR6, anticorps Tlr6

Sujet: Toll-like receptors (TLRs) are evolutionarily conserved pattern-recognition molecules resembling the toll proteins that mediate antimicrobial responses in Drosophila. These proteins recognize different microbial products during infection and serve as an important link between the innate and adaptive immune responses (1,2). The TLRs act through adaptor molecules such as MyD88 and TIRAP to activate various kinases and transcription factors (3) so the organism can respond to potential infection. TLR6 was first identified as a close homolog of TLR1, sharing 69 % sequence identify (4). Like TLR1, TLR6 can form heterodimers with TLR2, and these TLR6:TLR2 dimers coordinate macrophage activation by Gram-positive bacteria and the yeast cell wall particle zymosan (5). Activation of these complexes not only initiates pro-inflammatory cascades, but also can lead to apoptotic responses (6).Synonyms: Toll-like receptor 6

ID gène: 10333

NCBI Accession: NP_006059

Pathways: Signalisation TLR, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Toll-Like Receptors Cascades