Tel:
+49 (0)241 95 163 153
Fax:
+49 (0)241 95 163 155
E-Mail:
orders@anticorps-enligne.fr

TRAF6 anticorps (C-Term)

TRAF6 Reactivité: Humain, Souris, Rat WB, IF, EIA Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN501028
  • Antigène Voir toutes TRAF6 Anticorps
    TRAF6 (TNF Receptor-Associated Factor 6 (TRAF6))
    Épitope
    • 15
    • 9
    • 8
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reactivité
    • 58
    • 31
    • 25
    • 15
    • 5
    • 5
    • 4
    • 3
    • 2
    • 1
    • 1
    Humain, Souris, Rat
    Hôte
    • 56
    • 5
    • 2
    Lapin
    Clonalité
    • 54
    • 9
    Polyclonal
    Conjugué
    • 40
    • 4
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp TRAF6 est non-conjugé
    Application
    • 59
    • 18
    • 14
    • 13
    • 13
    • 11
    • 11
    • 10
    • 7
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (IF), Enzyme Immunoassay (EIA)
    Specificité
    This antibody detects TRAF6 / RNF85 at C-term.
    Réactivité croisée (Details)
    Species reactivity (tested):Human, mouse, rat
    Purification
    Ion exchange chromatography
    Immunogène
    TRAF6 antibody was raised against a peptide corresponding to 14 amino acids near the C- terminus of human TRAF6.
    Isotype
    IgG
    Top Product
    Discover our top product TRAF6 Anticorps primaire
  • Indications d'application
    ELISA. Western blot: 1 to 2 μg/mL. Immunflourescence.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Restrictions
    For Research Use only
  • Buffer
    PBS containing 0.02 % sodium azide
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Conseil sur la manipulation
    Avoid repeated freezing and thawing.
    Stock
    4 °C/-20 °C
    Stockage commentaire
    Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
  • Antigène
    TRAF6 (TNF Receptor-Associated Factor 6 (TRAF6))
    Autre désignation
    TRAF6 / RNF85 (TRAF6 Produits)
    Synonymes
    anticorps MGC:3310, anticorps RNF85, anticorps 2310003F17Rik, anticorps AI851288, anticorps C630032O20Rik, anticorps rnf85, anticorps traf6, anticorps xtraf6, anticorps CG10961, anticorps DTRAF2, anticorps Dmel\\CG10961, anticorps TRAF, anticorps TRAF2, anticorps TRAF6, anticorps Traf2, anticorps dTRAF2, anticorps dTRAF6, anticorps dTraf2, anticorps dtraf2, anticorps GB10539, anticorps fi15f02, anticorps wu:fi15f02, anticorps zgc:63704, anticorps TNF receptor associated factor 6, anticorps TNF receptor-associated factor 6, anticorps TNF receptor associated factor 6 L homeolog, anticorps TNF-receptor-associated factor 6, anticorps TNF receptor associated factor 6 S homeolog, anticorps TRAF6, anticorps Traf6, anticorps traf6.L, anticorps traf6, anticorps LOC551819, anticorps traf6.S
    Sujet
    Signals from the IL-1 receptor (IL-1R)/Toll-like receptor (TLR) and TNF receptor (TNFR) superfamilies are critical for regulating the function of antigen-presenting cells. Signals transduced by these molecules lead to increased expression and activation of transcription factors such as NF-?B (1,2). TNF receptor-associated factor 6 (TRAF6) is unique in that it is a signaling adapter molecule common to both families (3). TRAF6 is important in cytokine production, dendritic cell (DC) maturation, and the T cell stimulatory capacity of DCs in response to TLR and CD40 ligands (4). It can be activated in the IL-1R/TLR signaling pathway by IL-1 receptor-associated kinase 1 (IRAK-1) (5) or by other TLR adaptor molecules such as TRIF (6). Also, it has been shown that TRAF6 can interact directly with TNFR family members CD40 and RANK (7).Synonyms: Interleukin-1 signal transducer, RING finger protein 85, TNF receptor-associated factor 6
    ID gène
    7189
    NCBI Accession
    NP_004611
    Pathways
    Signalisation NF-kappaB, TCR Signaling, Signalisation TLR, Fc-epsilon Receptor Signaling Pathway, Neurotrophin Signaling Pathway, Activation of Innate immune Response, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Tube Formation, Hepatitis C, Toll-Like Receptors Cascades, Ubiquitin Proteasome Pathway
Vous êtes ici:
Support technique