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UBE2N anticorps (C-Term)

UBE2N Reactivité: Humain, Rat, Souris WB, IHC (p), EIA Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN501096
  • Antigène Voir toutes UBE2N Anticorps
    UBE2N (Ubiquitin-Conjugating Enzyme E2N (UBE2N))
    Épitope
    • 15
    • 5
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    C-Term
    Reactivité
    • 37
    • 33
    • 31
    • 5
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    Humain, Rat, Souris
    Hôte
    • 47
    • 4
    • 1
    Lapin
    Clonalité
    • 39
    • 13
    Polyclonal
    Conjugué
    • 21
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp UBE2N est non-conjugé
    Application
    • 19
    • 16
    • 13
    • 13
    • 7
    • 5
    • 4
    • 3
    • 2
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
    Specificité
    This antibody detects UBE2N / BLU.
    Réactivité croisée (Details)
    Species reactivity (tested):Human, mouse, rat
    Purification
    Ion exchange chromatography
    Immunogène
    UBC13 antibody was raised against a peptide corresponding to 15 amino acids near the C- terminus of human UBC13.
    Isotype
    IgG
    Top Product
    Discover our top product UBE2N Anticorps primaire
  • Indications d'application
    ELISA. Western blot. Immunohistochemistry on paraffin sections.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Restrictions
    For Research Use only
  • Buffer
    PBS containing 0.02 % sodium azide
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Conseil sur la manipulation
    Avoid repeated freezing and thawing.
    Stock
    4 °C/-20 °C
    Stockage commentaire
    Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
  • Antigène
    UBE2N (Ubiquitin-Conjugating Enzyme E2N (UBE2N))
    Abstract
    UBE2N Produits
    Synonymes
    anticorps UBC13, anticorps UbcH-ben, anticorps UbcH13, anticorps 1500026J17Rik, anticorps AL022654, anticorps BB101821, anticorps ube2n, anticorps wu:fb11b03, anticorps wu:fc08b06, anticorps zgc:55726, anticorps ubc13, anticorps ubch-ben, anticorps UBE2N, anticorps ube2nl, anticorps zgc:63901, anticorps ubiquitin conjugating enzyme E2 N, anticorps ubiquitin-conjugating enzyme E2N, anticorps ubiquitin conjugating enzyme E2 N S homeolog, anticorps ubiquitin-conjugating enzyme E2Na, anticorps ubiquitin-conjugating enzyme E2Nb, anticorps UBE2N, anticorps Ube2n, anticorps ube2n.S, anticorps ube2na, anticorps LOC100533434, anticorps ube2n, anticorps ube2nb
    Sujet
    Ubiquitin-conjugating enzyme 13 (Ubc13) was initially discovered in S. cerevisiae as a DNA-damage inducible protein involved in the error-free DNA postreplication repair pathway (1). It has recently been shown to be an important component of the Toll-like receptor and IL-1R signaling pathway (reviewed in 2). Signals from these pathways are relayed by a number of downstream molecules such as MyD88 and tumor necrosis factor receptor associated factor (TRAF6), ultimately activating various kinases and transcription factors (2,3). Ubc13 is part of a dimeric ubiquitin-conjugating enzyme complex also containing UEV1A (ubiquitin-conjugating enzyme E2 variant 1) that together with TRAF6 activates TAK1, a member of the mitogen-activated protein kinase kinase kinase family (4-6). The Ubc13-UEV1A complex also mediates the Lys-63 ubiquitination of TRAF-6, and this ubiquitination is essential for TAK1 activation (5).Synonyms: Bendless-like ubiquitin-conjugating enzyme, UBC13, Ubiquitin carrier protein N, Ubiquitin-conjugating enzyme E2 N, Ubiquitin-protein ligase N
    ID gène
    7334
    Pathways
    TCR Signaling, Fc-epsilon Receptor Signaling Pathway, Activation of Innate immune Response, Toll-Like Receptors Cascades, Positive Regulation of Response to DNA Damage Stimulus, Ubiquitin Proteasome Pathway
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