CTCFL anticorps (N-Term)

N° du produit ABIN501510

Détail du produit anti-CTCFL anticorps

Antigène: CTCFL (CCCTC-Binding Factor (Zinc Finger Protein)-Like (CTCFL))

Épitope: N-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CTCFL est non-conjugé

Application: Western Blotting (WB)

Séquence: CREKDHRSPS ELEAERTSGA FQDSVLEEEV ELVLAPSEES EKYILTLQTV

Homologie: Human: 100%

Attributs du produit: This is a rabbit polyclonal antibody against CTCFL. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human CTCFL

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 663 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Références pour anticorps anti-CTCFL (ABIN501510)

Sun, Huang, Nguyen, Bisht, Bar-Sela, Ho, Bradbury, Yu, Cui, Lee, Trepel, Feinberg, Gius: "DNA methyltransferase 1 and 3B activate BAG-1 expression via recruitment of CTCFL/BORIS and modulation of promoter histone methylation." dans: Cancer research, Vol. 68, Issue 8, pp. 2726-35, (2008) (PubMed).

Détails sur CTCFL

Antigène: CTCFL (CCCTC-Binding Factor (Zinc Finger Protein)-Like (CTCFL))

Autre désignation: CTCFL (CTCFL Produits)

Synonymes: anticorps BORIS, anticorps CT27, anticorps CTCF-T, anticorps HMGB1L1, anticorps dJ579F20.2, anticorps CTCFL, anticorps Boris, anticorps OTTMUSG00000016680, anticorps CCCTC-binding factor like, anticorps CCCTC-binding factor (zinc finger protein)-like, anticorps CTCFL, anticorps Ctcfl

Sujet: CCCTC-binding factor (CTCF), an 11-zinc-finger factor involved in gene regulation, utilizes different zinc fingers to bind varying DNA target sites. CTCF forms methylation-sensitive insulators that regulate X-chromosome inactivation. CTCFL is a paralog of CTCF and appears to be expressed primarily in the cytoplasm of spermatocytes, unlike CTCF which is expressed primarily in the nucleus of somatic cells. CTCF and CTCFL are normally expressed in a mutually exclusive pattern that correlates with resetting of methylation marks during male germ cell differentiation.CCCTC-binding factor (CTCF), an 11-zinc-finger factor involved in gene regulation, utilizes different zinc fingers to bind varying DNA target sites. CTCF forms methylation-sensitive insulators that regulate X-chromosome inactivation. This gene is a paralog of CTCF and appears to be expressed primarily in the cytoplasm of spermatocytes, unlike CTCF which is expressed primarily in the nucleus of somatic cells. CTCF and the protein encoded by this gene are normally expressed in a mutually exclusive pattern that correlates with resetting of methylation marks during male germ cell differentiation. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: BORIS, CTCF-T, MGC163358, dJ579F20.2, CT27, HMGB1L1
Protein Interaction Partner: SP1, BAG6, HIST2H2AC, HIST1H1A, PRMT7, HIST1H3A, BRCA1,
Protein Size: 663

Poids moléculaire: 76 kDa

ID gène: 140690

NCBI Accession: NM_080618, NP_542185

UniProt: Q8NI51