STAT5A anticorps (C-Term)
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- Antigène Voir toutes STAT5A Anticorps
- STAT5A (Signal Transducer and Activator of Transcription 5A (STAT5A))
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Épitope
- C-Term
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Reactivité
- Humain, Souris, Rat, Boeuf (Vache), Mouton, Porc, Chien, Cheval, Lapin, Chévre, Cobaye
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp STAT5A est non-conjugé
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Application
- Western Blotting (WB)
- Séquence
- DQAPSPAVCP QAPYNMYPQN PDHVLDQDGE FDLDETMDVA RHVEELLRRP
- Homologie
- Cow: 93%, Dog: 100%, Goat: 93%, Guinea Pig: 79%, Horse: 93%, Human: 100%, Mouse: 92%, Pig: 93%, Rabbit: 86%, Rat: 92%, Sheep: 93%
- Attributs du produit
- This is a rabbit polyclonal antibody against STAT5A. It was validated on Western Blot using a cell lysate as a positive control.
- Purification
- Affinity Purified
- Immunogène
- The immunogen is a synthetic peptide directed towards the C terminal region of human STAT5A
- Top Product
- Discover our top product STAT5A Anticorps primaire
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- Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator.
- Commentaires
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Antigen size: 794 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
- Stock
- -20 °C
- Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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Epigenetic control of rDNA loci in response to intracellular energy status." dans: Cell, Vol. 133, Issue 4, pp. 627-39, (2008) (PubMed).
: "
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Epigenetic control of rDNA loci in response to intracellular energy status." dans: Cell, Vol. 133, Issue 4, pp. 627-39, (2008) (PubMed).
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- Antigène
- STAT5A (Signal Transducer and Activator of Transcription 5A (STAT5A))
- Autre désignation
- STAT5A (STAT5A Produits)
- Synonymes
- anticorps MGF, anticorps STAT5, anticorps AA959963, anticorps Stat5, anticorps STAT5A/MGF, anticorps STATA5, anticorps STAT5A, anticorps stat5, anticorps stat5b, anticorps signal transducer and activator of transcription 5A, anticorps signal transducer and activator of transcription 5a, anticorps STAT5A, anticorps Stat5a, anticorps stat5a, anticorps LOC100348518, anticorps LOC100716811
- Sujet
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STAT5A is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein is activated by, and mediates the responses of many cell ligands, such as IL2, IL3, IL7 GM-CSF, erythropoietin, thrombopoietin, and different growth hormones. Activation of this protein in myeloma and lymphoma associated with a TEL/JAK2 gene fusion is independent of cell stimulus and has been shown to be essential for the tumorigenesis. The mouse counterpart of this gene is found to induce the expression of BCL2L1/BCL-X(L), which suggests the antiapoptotic function of this gene in cells. The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein is activated by, and mediates the responses of many cell ligands, such as IL2, IL3, IL7 GM-CSF, erythropoietin, thrombopoietin, and different growth hormones. Activation of this protein in myeloma and lymphoma associated with a TEL/JAK2 gene fusion is independent of cell stimulus and has been shown to be essential for the tumorigenesis. The mouse counterpart of this gene is found to induce the expression of BCL2L1/BCL-X(L), which suggests the antiapoptotic function of this gene in cells. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: MGF, STAT5
Protein Interaction Partner: TCF12, NLK, LEF1, NARF, CBL, UBC, ESR1, HELZ, UGT2B4, STAT5A, POM121C, WASH2P, AQP11, ZNF596, MRPS6, TXNDC11, RBMX, INSR, GLUD1, FN1, EPAS1, CYP2C9, CSNK2B, JAK2, BTK, EPOR, CRKL, SOCS7, NFKB1, ERBB4, EP300, MYB, SQSTM1, GNB2, SMARCA4, PGR, FGFR2, JAK3, C
Protein Size: 794 - Poids moléculaire
- 91 kDa
- ID gène
- 6776
- NCBI Accession
- NM_003152, NP_003143
- UniProt
- P42229
- Pathways
- Signalistation JAK/STAT, Signalisation RTK, Response to Growth Hormone Stimulus, C21-Steroid Hormone Metabolic Process, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, CXCR4-mediated Signaling Events, Activated T Cell Proliferation
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