SIM2 anticorps (N-Term)

N° du produit ABIN501700

Détail du produit anti-SIM2 anticorps

Antigène: SIM2 (Single-Minded Homolog 2 (SIM2))

Épitope: N-Term

Reactivité: Humain, Souris, Rat, Lapin, Chien, Cobaye, Cheval, Boeuf (Vache), Poisson zèbre (Danio rerio)

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SIM2 est non-conjugé

Application: Western Blotting (WB)

Séquence: MKEKSKNAAK TRREKENGEF YELAKLLPLP SAITSQLDKA SIIRLTTSYL

Homologie: Cow: 93%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%

Attributs du produit: This is a rabbit polyclonal antibody against SIM2. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human SIM2

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 667 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Références pour anticorps anti-SIM2 (ABIN501700)

Spellman, Ahmed, Dubach, Gardiner: "Expression of trisomic proteins in Down syndrome model systems." dans: Gene, Vol. 512, Issue 2, pp. 219-25, (2012) (PubMed).

Détails sur SIM2

Antigène: SIM2 (Single-Minded Homolog 2 (SIM2))

Autre désignation: SIM2 (SIM2 Produits)

Synonymes: anticorps Xsim2, anticorps sim2-A, anticorps xSim, anticorps HMC13F06, anticorps HMC29C01, anticorps SIM, anticorps bHLHe15, anticorps single-minded family bHLH transcription factor 2 S homeolog, anticorps single-minded family bHLH transcription factor 2, anticorps single-minded homolog 2 (Drosophila), anticorps sim2.S, anticorps sim2, anticorps SIM2, anticorps Sim2

Sujet: SIM1 and SIM2 genes are Drosophila single-minded (sim) gene homologs. The Drosophila sim gene encodes a transcription factor that is a master regulator of fruit fly neurogenesis. SIM2 maps within the so-called Down syndrome chromosomal region. Based on t
Alias Symbols: MGC119447, SIM, bHLHe15, HMC13F06, HMC29C01
Protein Interaction Partner: Dlg4, HSP90AA1, ARIH1, UBC, PARK2, ARNT, ARNT2, EPO,
Protein Size: 667

Poids moléculaire: 73 kDa

ID gène: 6493

NCBI Accession: NM_005069, NP_005060

UniProt: Q14190