MEF2A anticorps (N-Term)

N° du produit ABIN501715

Détail du produit anti-MEF2A anticorps

Antigène: MEF2A (Myocyte Enhancer Factor 2A (MEF2A))

Épitope: N-Term

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Cheval, Chien, Lapin, Cobaye, Poisson zèbre (Danio rerio), Mouton

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MEF2A est non-conjugé

Application: Western Blotting (WB)

Séquence: GRKKIQITRI MDERNRQVTF TKRKFGLMKK AYELSVLCDC EIALIIFNSS

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Sheep: 100%, Zebrafish: 100%

Attributs du produit: This is a rabbit polyclonal antibody against MEF2A. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human MEF2A

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 507 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur MEF2A

Antigène: MEF2A (Myocyte Enhancer Factor 2A (MEF2A))

Autre désignation: MEF2A (MEF2A Produits)

Synonymes: anticorps ADCAD1, anticorps RSRFC4, anticorps RSRFC9, anticorps mef2, anticorps A430079H05Rik, anticorps mef2a, anticorps wu:fd19d02, anticorps adcad1, anticorps rsrfc4, anticorps rsrfc9, anticorps sl2, anticorps MEF2A, anticorps xmef2a, anticorps myocyte enhancer factor 2A, anticorps myocyte enhancer factor 2aa, anticorps myocyte enhancer factor 2a, anticorps myocyte-specific enhancer factor 2A, anticorps myocyte-specific enhancer factor 2a, putative, anticorps myocyte enhancer factor 2A L homeolog, anticorps MEF2A, anticorps Mef2a, anticorps mef2aa, anticorps EDI_092490, anticorps EDI_038250, anticorps Smp_161530, anticorps mef2a.L, anticorps mef2a, anticorps LOC539054

Sujet: The MEF2 genes are members of the MADS gene family (named for the yeast mating type-specific transcription factor MCM1, the plant homeotic genes 'agamous' and 'deficiens' and the human serum response factor SRF (MIM 600589)),a family that also includes several homeotic genes and other transcription factors, all of which share a conserved DNA-binding domain. The process of differentiation from mesodermal precursor cells to myoblasts has led to the discovery of a variety of tissue-specific factors that regulate muscle gene expression. The myogenic basic helix-loop-helix proteins, including myoD (MIM159970), myogenin (MIM 159980), MYF5 (MIM 159990), and MRF4 (MIM159991) are one class of identified factors. A second family of DNA binding regulatory proteins is the myocyte-specific enhancer factor-2 (MEF2) family. Each of these proteins binds to the MEF2 target DNA sequence present in the regulatory regions of many, if not all, muscle-specific genes. The MEF2 genes are members of the MADS gene family (named for the yeast mating type-specific transcription factor MCM1, the plant homeotic genes 'agamous' and 'deficiens' and the human serum response factor SRF (MIM 600589)),a family that also includes several homeotic genes and other transcription factors, all of which share a conserved DNA-binding domain.The process of differentiation from mesodermal precursor cells to myoblasts has led to the discovery of a variety of tissue-specific factors that regulate muscle gene expression. The myogenic basic helix-loop-helix proteins, including myoD (MIM 159970), myogenin (MIM 159980), MYF5 (MIM 159990), and MRF4 (MIM 159991) are one class of identified factors. A second family of DNA binding regulatory proteins is the myocyte-specific enhancer factor-2 (MEF2) family. Each of these proteins binds to the MEF2 target DNA sequence present in the regulatory regions of many, if not all, muscle-specific genes. The MEF2 genes are members of the MADS gene family (named for the yeast mating type-specific transcription factor MCM1, the plant homeotic genes 'agamous' and 'deficiens' and the human serum response factor SRF (MIM 600589)), a family that also includes several homeotic genes and other transcription factors, all of which share a conserved DNA-binding domain.[supplied by OMIM]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: ADCAD1, RSRFC4, RSRFC9, mef2
Protein Interaction Partner: HDAC7, HDAC5, HDAC3, TAF8, GNG12, TBP, GNB2, ERBB2IP, NDUFB9, DDB1, Dlg4, PHB2, ASCL1, SUMO1, UBE2I, SUMO2, HNRNPA1, UBC, MEF2D, HDAC1, EP300, HDAC4, ACTN4, THRA, HDAC9, MAPK7, CASP7, SMAD2, SMAD4, MEF2A, CASP3, MAPK14, TEAD1, MYOG, MYOD1, CDK5, VGLL4,
Protein Size: 507

Poids moléculaire: 55 kDa

ID gène: 4205

NCBI Accession: NM_005587, NP_005578

UniProt: Q02078

Pathways: Neurotrophin Signaling Pathway, Activation of Innate immune Response, Carbohydrate Homeostasis, Chromatin Binding, Regulation of Muscle Cell Differentiation, Toll-Like Receptors Cascades