FBXW11 anticorps (N-Term)

N° du produit ABIN502384

Détail du produit anti-FBXW11 anticorps

Antigène: FBXW11 (F-Box and WD Repeat Domain Containing 11 (FBXW11))

Épitope: N-Term

Reactivité: Humain, Souris, Rat, Chien, Boeuf (Vache), Cobaye, Lapin

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp FBXW11 est non-conjugé

Application: Western Blotting (WB)

Séquence: EPDSVIEDKT IELMNTSVME DQNEDESPKK NTLWQISNGT SSVIVSRKRP

Homologie: Cow: 93%, Dog: 100%, Guinea Pig: 100%, Human: 100%, Mouse: 86%, Rabbit: 100%, Rat: 100%

Attributs du produit: This is a rabbit polyclonal antibody against FBXW11. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human FBXW11

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 529 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Références pour anticorps anti-FBXW11 (ABIN502384)

Ewing, Chu, Elisma, Li, Taylor, Climie, McBroom-Cerajewski, Robinson, OConnor, Li, Taylor, Dharsee, Ho, Heilbut, Moore, Zhang, Ornatsky, Bukhman, Ethier, Sheng, Vasilescu, Abu-Farha, Lambert, Duewel et al.: "Large-scale mapping of human protein-protein interactions by mass spectrometry. ..." dans: Molecular systems biology, Vol. 3, pp. 89, (2007) (PubMed).

Détails sur FBXW11

Antigène: FBXW11 (F-Box and WD Repeat Domain Containing 11 (FBXW11))

Autre désignation: FBXW11 (FBXW11 Produits)

Synonymes: anticorps BTRC2, anticorps BTRCP2, anticorps FBW1B, anticorps FBXW1B, anticorps Fbw11, anticorps Hos, anticorps 2310065A07Rik, anticorps AA536858, anticorps Fbxw1b, anticorps HOS, anticorps btrc2, anticorps fbxw11a, anticorps wu:fa12e12, anticorps wu:fb11f03, anticorps zgc:63728, anticorps fbxw11, anticorps fbxw11b, anticorps fbxw1b, anticorps wu:fd14d12, anticorps wu:fi43f07, anticorps F-box and WD repeat domain containing 11, anticorps F-box and WD-40 domain protein 11, anticorps F-box/WD repeat-containing protein 11, anticorps F-box and WD repeat domain containing 11b, anticorps F-box and WD repeat domain containing 11a, anticorps FBXW11, anticorps Fbxw11, anticorps LOC100199403, anticorps fbxw11b, anticorps fbxw11a

Sujet: FBXW11 is a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbws class and, in addition to an F-box, contains multiple WD40 repeats.This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbws class and, in addition to an F-box, contains multiple WD40 repeats. This gene contains at least 14 exons, and its alternative splicing generates 3 transcript variants diverging at the presence/absence of two alternate exons.
Alias Symbols: BTRC2, BTRCP2, FBW1B, FBXW1B, Fbw11, Hos, KIAA0696
Protein Interaction Partner: ELMO2, NCKAP5L, USP37, CACHD1, ZNF395, TACC1, STK4, STK3, SKP1, REST, RELA, RAP1GAP, PFDN5, PFDN4, NRD1, NFKB2, NFKB1, NFE2L2, NEDD8, MAX, LRCH4, ILF3, FOXN2, HNRNPU, HIVEP2, HIVEP1, HCFC1, EZH2, DOCK1, DHX9, CTNNB1, CTNNA1, CLTC, CHD1, CDC34, CDC25B, CDC
Protein Size: 529

Poids moléculaire: 61 kDa

ID gène: 23291

NCBI Accession: NM_033644, NP_387448

UniProt: Q9UKB1