IL1RL2 anticorps (AA 1-203)

N° du produit ABIN5027302

Détail du produit anti-IL1RL2 anticorps

Antigène: IL1RL2 (Interleukin 1 Receptor-Like 2 (IL1RL2))

Épitope: AA 1-203

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp IL1RL2 est non-conjugé

Application: Western Blotting (WB)

Purification: Protein G Chromatography

Immunogène: A partial length recombinant IL-36R protein (amino acids 1-203) was used as the immunogen for this antibody.

Clone: ABM47A2

Isotype: IgG2b

Information d'application

Indications d'application: WB: 2-4 μg/mL

Restrictions: For Research Use only

Stockage

Concentration: 0.5 mg/mL

Buffer: PBS containing 0.05 % BSA, PH 7.4

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.

Détails sur IL1RL2

Antigène: IL1RL2 (Interleukin 1 Receptor-Like 2 (IL1RL2))

Autre désignation: IL-36R (IL1RL2 Produits)

Sujet: IL-36R is a member of the IL-1 receptor family that has been associated with various inflammation-associated diseases. Ligands binding to IL-36R subsequently recruit the IL-1RAcP (IL-1 Receptor Accessory Protein) forming a heterodimeric signaling complex. The latter is also used by IL-1Alpha and IL-1Beta. IL-36R is expressed by different immune cells, including Dendritic Cells, microglia and other myeloid cells. IL-36 stimulation of DC leads to the production of several cytokines by DC, including TNF-a, IL-1, IL-12, and IL-23. This interaction also enhances the expression of MHC class 2 and co-stimulatory molecules.

Poids moléculaire: 69 kDa

ID gène: 8808

UniProt: Q9HB29