NNT anticorps (N-Term)

N° du produit ABIN502788

Détail du produit anti-NNT anticorps

Antigène: NNT (Nicotinamide Nucleotide Transhydrogenase (NNT))

Épitope: N-Term

Reactivité: Humain, Souris, Rat, Chien, Boeuf (Vache), Poisson zèbre (Danio rerio), Cobaye, Cheval, Lapin

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp NNT est non-conjugé

Application: Western Blotting (WB)

Séquence: IVRGFDTRAA ALEQFKSLGA EPLEVDLKES GEGQGGYAKE MSKEFIEAEM

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 93%

Attributs du produit: This is a rabbit polyclonal antibody against NNT. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human NNT

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 1086 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Références pour anticorps anti-NNT (ABIN502788)

Mehrle, Rosenfelder, Schupp, del Val, Arlt, Hahne, Bechtel, Simpson, Hofmann, Hide, Glatting, Huber, Pepperkok, Poustka, Wiemann: "The LIFEdb database in 2006." dans: Nucleic acids research, Vol. 34, Issue Database issue, pp. D415-8, (2005) (PubMed).

Détails sur NNT

Antigène: NNT (Nicotinamide Nucleotide Transhydrogenase (NNT))

Autre désignation: NNT (NNT Produits)

Synonymes: anticorps Afu5g02780, anticorps GCCD4, anticorps 4930423F13Rik, anticorps AI323702, anticorps BB168308, anticorps wu:fa20d10, anticorps wu:fc86a04, anticorps zgc:76979, anticorps Nicotinamide Nucleotide Transhydrogenase, anticorps nicotinamide nucleotide transhydrogenase, anticorps nicotinamide nucleotide transhydrogenase L homeolog, anticorps nnt-1, anticorps AFUA_5G02780, anticorps nnt, anticorps NNT, anticorps Nnt, anticorps nnt.L

Sujet: NNT is an integral protein of the inner mitochondrial membrane. The enzyme couples hydride transfer between NAD(H) and NADP(+) to proton translocation across the inner mitochondrial membrane. Under most physiological conditions, the enzyme uses energy from the mitochondrial proton gradient to produce high concentrations of NADPH. The resulting NADPH is used for biosynthesis and in free radical detoxification. This gene encodes an integral protein of the inner mitochondrial membrane. The enzyme couples hydride transfer between NAD(H) and NADP(+) to proton translocation across the inner mitochondrial membrane. Under most physiological conditions, the enzyme uses energy from the mitochondrial proton gradient to produce high concentrations of NADPH. The resulting NADPH is used for biosynthesis and in free radical detoxification. Two alternatively spliced variants, encoding the same protein, have been found for this gene.
Alias Symbols: MGC126502, MGC126503
Protein Interaction Partner: MVP, UBC, TIMM10, PTCD1, FKBP8, POFUT1, UQCR11, ATP6V1F, PRPF3, LAMTOR3, SF1, THY1, ABCD3, NDUFS6, NDUFA9, SLC26A2, ATP5B, SLC25A6, SIRT7, MME, HNRNPA1,
Protein Size: 1086

Poids moléculaire: 114 kDa

ID gène: 23530

NCBI Accession: NM_012343, NP_036475

UniProt: Q13423

Pathways: Proton Transport