URI1 anticorps (Middle Region)

N° du produit ABIN503187

Détail du produit anti-URI1 anticorps

Antigène: URI1 (URI1, Prefoldin-Like Chaperone (URI1))

Épitope: Middle Region

Reactivité: Humain, Souris, Rat, Chien, Boeuf (Vache), Cheval, Lapin, Cobaye

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp URI1 est non-conjugé

Application: Western Blotting (WB)

Séquence: NGEYVPRKSI LKSRSRENSV CSDTSESSAA EFDDRRGVLR SISCEEATCS

Homologie: Cow: 93%, Dog: 86%, Guinea Pig: 93%, Horse: 86%, Human: 100%, Mouse: 79%, Rabbit: 100%, Rat: 80%

Attributs du produit: This is a rabbit polyclonal antibody against C19orf2. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of human C19orf2

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 495 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur URI1

Antigène: URI1 (URI1, Prefoldin-Like Chaperone (URI1))

Autre désignation: C19orf2 (URI1 Produits)

Synonymes: anticorps c19orf2, anticorps C19orf2, anticorps NNX3, anticorps PPP1R19, anticorps RMP, anticorps URI, anticorps URI1 prefoldin-like chaperone L homeolog, anticorps URI1, prefoldin like chaperone, anticorps uri1.L, anticorps URI1

Sujet: The function of the C19orf2 protein remains unknown.The protein encoded by this gene binds to RNA polymerase II subunit 5 (RPB5) and negatively modulates transcription through its binding to RPB5. The encoded protein seems to have inhibitory effects on various types of activated transcription, but it requires the RPB5-binding region. This protein acts as a corepressor. It is suggested that it may require signaling processes for its function or that it negatively modulates genes in the chromatin structure. Two alternatively spliced transcript variants encoding different isoforms have been described for this gene.
Alias Symbols: FLJ10575, NNX3, RMP, URI, C19orf2, PPP1R19
Protein Interaction Partner: RPAP3, UBC, ITCH, NEDD4, ATF7, TTI1, RUVBL1, RPS6KB1, PPP1CC, HSP90AA1, APP, UXT, RPAP2, GPN1, RUVBL2, STAP1, POLR2E, URI1, DMAP1, GTF2F2,
Protein Size: 495

Poids moléculaire: 55 kDa

ID gène: 8725

NCBI Accession: NM_134447, NP_604431

UniProt: Q6NX55