SMG5 anticorps (N-Term)

N° du produit ABIN503664

Détail du produit anti-SMG5 anticorps

Antigène: SMG5 (Smg-5 Homolog, Nonsense Mediated mRNA Decay Factor (SMG5))

Épitope: N-Term

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Cobaye, Cheval, Porc, Chien

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SMG5 est non-conjugé

Application: Western Blotting (WB)

Séquence: MSQGPPTGES SEPEAKVLHT KRLYRAVVEA VHRLDLILCN KTAYQEVFKP

Homologie: Cow: 100%, Dog: 93%, Guinea Pig: 86%, Horse: 93%, Human: 100%, Mouse: 93%, Pig: 93%, Rat: 86%

Attributs du produit: This is a rabbit polyclonal antibody against SMG5. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human SMG5

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 1016 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur SMG5

Antigène: SMG5 (Smg-5 Homolog, Nonsense Mediated mRNA Decay Factor (SMG5))

Autre désignation: SMG5 (SMG5 Produits)

Synonymes: anticorps BC024683, anticorps mKIAA1089, anticorps EST1B, anticorps LPTS-RP1, anticorps LPTSRP1, anticorps SMG-5, anticorps SMG5, nonsense mediated mRNA decay factor, anticorps Smg-5 homolog, nonsense mediated mRNA decay factor (C. elegans), anticorps SMG5 nonsense mediated mRNA decay factor, anticorps SMG5, anticorps Smg5

Sujet: SMG5 plays a role in nonsense-mediated mRNA decay. SMG5 does not have RNase activity by itself. SMG5 promotes dephosphorylation of RENT1. SMG5 is necessary for TERT activity.SMG5 is involved in nonsense-mediated mRNA decay (Ohnishi et al., 2003 [PubMed 14636577]).[supplied by OMIM].
Alias Symbols: EST1B, FLJ34864, KIAA1089, LPTS-RP1, LPTSRP1, RP11-54H19.7, SMG-5
Protein Interaction Partner: RBM8A, UPF1, PHB, ZWINT, UBC, APP, HDAC8, STUB1, SMG7, SMG6, SMG1, TERT,
Protein Size: 1016

Poids moléculaire: 114 kDa

ID gène: 23381

NCBI Accession: NM_015327, NP_056142

UniProt: Q9UPR3