ATP6V1B2 anticorps (N-Term)

N° du produit ABIN503925

Détail du produit anti-ATP6V1B2 anticorps

Antigène: ATP6V1B2 (ATPase, H+ Transporting, Lysosomal 56/58kDa, V1 Subunit B2 (ATP6V1B2))

Épitope: N-Term

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Chien, Lapin, Cobaye, Poisson zèbre (Danio rerio)

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ATP6V1B2 est non-conjugé

Application: Western Blotting (WB)

Séquence: VSRNYLSQPR LTYKTVSGVN GPLVILDHVK FPRYAEIVHL TLPDGTKRSG

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 85%

Attributs du produit: This is a rabbit polyclonal antibody against ATP6V1B2. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human ATP6V1B2

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 511 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur ATP6V1B2

Antigène: ATP6V1B2 (ATPase, H+ Transporting, Lysosomal 56/58kDa, V1 Subunit B2 (ATP6V1B2))

Autre désignation: ATP6V1B2 (ATP6V1B2 Produits)

Synonymes: anticorps Atp6b1b2, anticorps Atp6b2, anticorps Vatb, anticorps vha55, anticorps VATB, anticorps ATP6B1B2, anticorps ATP6B2, anticorps HO57, anticorps VPP3, anticorps Vma2, anticorps atp6v1bb, anticorps fj51e01, anticorps vatB2, anticorps wu:fj51e01, anticorps zgc:109771, anticorps AI194269, anticorps AI790362, anticorps R74844, anticorps ATPase H+ transporting V1 subunit B2, anticorps ATPase, H+ transporting, lysosomal 56/58kDa, V1 subunit B2 S homeolog, anticorps ATPase, H+ transporting, lysosomal, V1 subunit B2, anticorps ATPase, H+ transporting, lysosomal V1 subunit B2, anticorps Atp6v1b2, anticorps atp6v1b2.S, anticorps ATP6V1B2, anticorps atp6v1b2

Sujet: ATP6V1B2 is a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of eukaryotic intracellular organelles. V-ATPase dependent organelle acidification is necessary for such intracellular processes as protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation. V-ATPase is composed of a cytosolic V1 domain and a transmembrane V0 domain. The V1 domain consists of three A, three B, and two G subunits, as well as a C, D, E, F, and H subunit. The V1 domain contains the ATP catalytic site. ATP6V1B2 is one of two V1 domain B subunit isoforms and is the only B isoform highly expressed in osteoclasts.This gene encodes a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of eukaryotic intracellular organelles. V-ATPase dependent organelle acidification is necessary for such intracellular processes as protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation. V-ATPase is composed of a cytosolic V1 domain and a transmembrane V0 domain. The V1 domain consists of three A, three B, and two G subunits, as well as a C, D, E, F, and H subunit. The V1 domain contains the ATP catalytic site. The protein encoded by this gene is one of two V1 domain B subunit isoforms and is the only B isoform highly expressed in osteoclasts. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: ATP6B1B2, ATP6B2, HO57, VATB, VPP3, Vma2
Protein Interaction Partner: TCF4, UBC, PBDC1, GMPPB, GANAB, SWAP70, MSH2, JUP, MSH6, XRCC6, CRMP1, HYOU1, SEC24C, CUL2, SUPT5H, SSRP1, PDE3A, CSDE1, PAN2, FN1, SRXN1, YIF1B, UNK, ZFYVE19, TUBA1C, INTS2, TRMT1, ABCF3, ATP6V1H, CCT8, SSSCA1, TUBB4B, UBA2, USP34, ATP6V1F, ZBED1, ZPR1,
Protein Size: 511

Poids moléculaire: 56 kDa

ID gène: 526

NCBI Accession: NM_001693, NP_001684

UniProt: P21281

Pathways: Transition Metal Ion Homeostasis, Proton Transport